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BRE 抗体

BRE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2423009
发货至: 中国
  • 抗原 See all BRE 抗体
    BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 40
    • 2
    克隆类型
    • 42
    多克隆
    标记
    • 18
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    This BRE antibody is un-conjugated
    应用范围
    • 31
    • 13
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    • 7
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    • 2
    • 1
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human BRE
    亚型
    IgG
    Top Product
    Discover our top product BRE Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    Avoid freeze / thaw cycles.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
    别名
    BABAM2 (BRE 产品)
    别名
    brcc4 antibody, brcc45 antibody, BRE antibody, LOC100231620 antibody, BRCC4 antibody, BRCC45 antibody, 6030405P19Rik antibody, AI429776 antibody, B830038C02Rik antibody, im:7141046 antibody, zgc:110368 antibody, BRISC and BRCA1 A complex member 2 antibody, brain and reproductive organ-expressed (TNFRSF1A modulator) antibody, BRISC and BRCA1 A complex member 2 L homeolog antibody, babam2 antibody, BABAM2 antibody, Babam2 antibody, BRE antibody, babam2.L antibody
    背景
    Brain and reproductive organ-expressed protein (BRE) is a 415 amino acid protein which binds to the intracellular juxtamembrane domain of the death receptor, tumor necrosis factor receptor 1 (TNF-R1). BRE also binds to the death receptor, FAS. BRE downregulates TNFa-induced activation of NFkB and may play a role in homeostasis or cellular differentiation in cells of epithelial, neural and germ line origins. It inhibits components of the death-inducing signaling complexes that are necessary for activation of the mitochondria, thereby mediating apoptosis. BRE is strongly expressed in the adrenal cortex, medulla, testis and pancreas, and is weakly expressed in the thymus, thyroid, stomach and small intestine.
    分子量
    Calculated MW: 44 kDa
    途径
    Positive Regulation of Response to DNA Damage Stimulus
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