-
- 抗原 See all Selenoprotein W (SEPW1) 抗体
- Selenoprotein W (SEPW1) (Selenoprotein W, 1 (SEPW1))
-
适用
- 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Selenoprotein W antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 特异性
- This product was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific for mouse Selenoprotein W. A BLAST analysis was used to suggest cross-reactivity with SelW from rat based on a 98% homology with the immunizing sequence. Partial reactivity is expected against human-derived SelW based on an 87% homology with the immunogen. Cross-reactivity with SelW from other sources has not been determined.
- 产品特性
- This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Selenoprotein W was first purified and characterized from rat skeletal muscle. The function of selenoprotein W is not entirely clear, but the presence of the bound glutathione moiety indicates that SelW is thought to function in oxidation-reduction catalysis and may play a role in selenium deficiency disorders such as white muscle disease in sheep and Keshan disease in humans. Recently, overexpression of SelW was shown to be glutathione dependent and was shown to markedly reduce the sensitivity of cell lines to H2O2 cytotoxicity.
- 纯化方法
- affinity purified
- 过滤
- Sterile filtered
- 免疫原
-
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to full-length mouse SelW protein.
Immunogen Type: RecombinantProtein - 亚型
- IgG
-
anti-Selenoprotein W, 1 (SEPW1) (AA 13-88) antibody
SEPW1 适用: 大鼠 WB, ELISA, IF (p), IF (cc), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Selenoprotein W, 1 (SEPW1) (AA 1-86) antibodySEPW1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 9.6 kDa in size corresponding to SelW by western blotting in the appropriate cell lysate or extract. This antibody is capable of detecting both overexpressed and endogenous SelW.
- 说明
-
Gene Name: SEPW1
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1.38 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is three (3) months from date of opening.
- 有效期
- 3 months
-
- 抗原
- Selenoprotein W (SEPW1) (Selenoprotein W, 1 (SEPW1))
- 别名
- Selenoprotein W (SEPW1 产品)
- 别名
- SEPW1 antibody, sepw1 antibody, selw1 antibody, SelW antibody, selW antibody, SEPW antibody, cb694 antibody, fe37b06 antibody, wu:fe37b06 antibody, wu:fk70h03 antibody, zgc:109781 antibody, selenoprotein W antibody, selenoprotein W, 1 antibody, SELENOW antibody, sepw1 antibody, Selenow antibody, SEPW1 antibody, selenow1 antibody
- 背景
-
This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Selenoprotein W was first purified and characterized from rat skeletal muscle. The function of selenoprotein W is not entirely clear, but the presence of the bound glutathione moiety indicates that SelW is thought to function in oxidation–reduction catalysis and may play a role in selenium deficiency disorders such as white muscle disease in sheep and Keshan disease in humans. Recently, overexpression of SelW was shown to be glutathione dependent and was shown to markedly reduce the sensitivity of cell lines to H2O2 cytotoxicity.
Synonyms: Selenoprotein W SelW - 基因ID
- 20364, 2384723
- UniProt
- P63300
- 途径
- Cell RedoxHomeostasis
-
You are here:
