(3 references)-
- 抗原 See all TNFRSF1B 抗体
- TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNFRSF1B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), Immunoassay (IA)
- 交叉反应 （详细）
- Cross reactivity: Mouse TNF-RI : Yes, Mouse TNF-alpha Minimal crossreactivity problematic in case of TNF-RII knockout studies and when used in high concentrations in functional studies
- 过滤
- 0.2 μm filtered
- 亚型
- IgG
- Top Product
- Discover our top product TNFRSF1B Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) (AA 23-257) antibody
TNFRSF1B 适用: 人, 小鼠 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 2H11C2 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) (AA 23-257) antibodyTNFRSF1B 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 7G8B6 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) antibodyTNFRSF1B 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) (C-Term) antibodyTNFRSF1B 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) (N-Term) antibodyTNFRSF1B 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) (AA 30-250) antibodyTNFRSF1B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) (C-Term) antibodyTNFRSF1B 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) (AA 1-461) antibodyTNFRSF1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) antibodyTNFRSF1B 适用: 人 WB, ELISA, IHC, IHC (p), Neut 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B) antibody (Biotin)TNFRSF1B 适用: 小鼠 WB, FACS, IP, Func, IA 宿主: 大鼠 Monoclonal HM102 Biotin
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- 应用备注
- For flow cytometry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental setting.
- 限制
- 仅限研究用
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- 缓冲液
- PBS, containing 0.1 % bovine serum albumin
- 储存条件
- 4 °C
- 储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
- 有效期
- 12 months
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: "Detection of membrane-bound tumor necrosis factor (TNF): an analysis of TNF-specific reagents." in: Microscopy research and technique, Vol. 50, Issue 3, pp. 243-50, (2000) (PubMed).
: "Both TNF receptors are required for direct TNF-mediated cytotoxicity in microvascular endothelial cells." in: European journal of immunology, Vol. 28, Issue 11, pp. 3577-86, (1998) (PubMed).
: "LPS-induced sTNF-receptor release in vivo in a murine model. Investigation of the role of tumor necrosis factor, IL-1, leukemia inhibiting factor, and IFN-gamma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 10, pp. 5554-62, (1993) (PubMed).
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: "Detection of membrane-bound tumor necrosis factor (TNF): an analysis of TNF-specific reagents." in: Microscopy research and technique, Vol. 50, Issue 3, pp. 243-50, (2000) (PubMed).
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- 抗原
- TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
- 别名
- Cd120b, Tnf-Rii (TNFRSF1B 产品)
- 别名
- CD120b antibody, TBPII antibody, TNF-R-II antibody, TNF-R75 antibody, TNFBR antibody, TNFR1B antibody, TNFR2 antibody, TNFR80 antibody, p75 antibody, p75TNFR antibody, TNF-RII/TNFRSF1B antibody, TNFR-II antibody, TNFRSF1B antibody, TNF-R2 antibody, TNF-alphaR2 antibody, TNFRII antibody, TNFalpha-R2 antibody, Tnfr-1 antibody, Tnfr2 antibody, rank antibody, zgc:163064 antibody, TNF receptor superfamily member 1B antibody, tumor necrosis factor receptor superfamily, member 1b antibody, tumor necrosis factor receptor superfamily, member 1B antibody, TNFRSF1B antibody, Tnfrsf1b antibody, tnfrsf1b antibody
- 背景
- The polyclonal antibody recognizes the extracellular part of the mouse Tumor Necrosis Factor Receptor type 2 (TNF-RII) of the membrane-bound as well as the soluble receptor. TNF-RII (~75-80 kDa) is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha. TNF-alpha activates inflammatory responses, induces apoptosis, regulates cellular proliferation, and may even promote cancer progression. The effects of TNF-alpha are mediated by TNF-RI and TNF-RII, which have both distinct and overlapping downstream signaling cascades. Induction of cytotoxicity and other functions are mediated largely via TNF-RI. TNF-RI is equally well activated by both the 17 kDa soluble and 26 kDa membrane-bound form, whereas TNF-RII is efficiently activated only by the membrane bound form of TNF-alpha. Binding of the inherently trimeric TNF-alpha to TNFR1 and TNFR2 induces receptor trimerization and recruitment of several signaling proteins to the cytoplasmic domains of the receptors. Occupancy of TNFR2 results in direct recruitment of TNF Receptor Associated Factor 2 (TRAF2), which in turn recruits TRAF1. Aliases Tumor necrosis factor receptor superfamily member 1B, TNF-RII, p75/p80
- 途径
- NF-kappaB Signaling, Apoptosis, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway
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