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C3AR1 抗体

C3AR1 适用: 人 FACS, IHC (fro) 宿主: 小鼠 Monoclonal 17 (hC3aRZ8) unconjugated
产品编号 ABIN2192050
发货至: 中国
  • 抗原 See all C3AR1 抗体
    C3AR1 (Complement Component 3a Receptor 1 (C3AR1))
    适用
    • 42
    • 16
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    宿主
    • 33
    • 18
    小鼠
    克隆类型
    • 32
    • 18
    • 1
    单克隆
    标记
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    This C3AR1 antibody is un-conjugated
    应用范围
    • 24
    • 24
    • 14
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    • 7
    • 7
    • 3
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    过滤
    0.2 μm filtered
    克隆位点
    17 (hC3aRZ8)
    Top Product
    Discover our top product C3AR1 Primary Antibody
  • 应用备注
    is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    限制
    仅限研究用
  • 缓冲液
    PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    C3AR1 (Complement Component 3a Receptor 1 (C3AR1))
    Abstract
    C3AR1 产品
    别名
    C3AR antibody, C3a-R antibody, c3ar1 antibody, AZ3B antibody, HNFAG09 antibody, C3a anaphylatoxin chemotactic receptor antibody, complement C3a receptor 1 antibody, complement component 3a receptor 1 antibody, c3ar1 antibody, C3AR1 antibody, C3ar1 antibody
    背景
    The monoclonal antibody 17 reacts with the human receptor for C3a. The monoclonal antibody 17 is in the literature also referred to as clone hC3aRZ8. In the course of complement activation the C3a receptor functions as the cell surface receptor for the anaphylatoxin C3a, the C-terminal 77 amino acid cleavage product of the alpha chain of C3, but not for C3a-desArg. All cellular responses to C3a are specifically mediated by interactions with the membrane bound C3a receptor, a seven transmembrane GTP-binding-protein-coupled receptor that belongs to the rhodopsin supergene family. The 54 kDa C3a receptor is widely distributed in, myeloid cells, peripheral tissues and the central nervous system. Expression of C3aR has been demonstrated on neutrophils, monocytes, eosinophils, astrocytes, neurons and glial cells and is increased in inflammatory conditions. No C3aR expression was detectable on lymphocytes and on tonsillar B cells even after stimulation.
    途径
    Complement System
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