Complement Factor H 抗体 (FITC)
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- 抗原 See all Complement Factor H (CFH) 抗体
- Complement Factor H (CFH)
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适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Complement Factor H antibody is conjugated to FITC
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunoassay (IA)
- 交叉反应 （详细）
- Cross reactivity: (Yes/No) Rat : Yes
- 过滤
- 0.2 μm filtered
- 克隆位点
- 1A2
- 亚型
- IgG1
- Top Product
- Discover our top product CFH Primary Antibody
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anti-Complement Factor H (CFH) (AA 20-270) antibody
CFH 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor H (CFH) (AA 915-1156) antibodyCFH 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor H (CFH) (Internal Region) antibodyVerified CFH 适用: 人 WB, IHC, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Complement Factor H (CFH) (AA 860-1231) antibodyCFH 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor H (CFH) (AA 975-1217) antibodyCFH 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor H (CFH) (AA 751-780) antibodyCFH 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB18698 unconjugated
anti-Complement Factor H (CFH) (N-Term) antibodyCFH 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor H (CFH) (AA 20-270) antibodyCFH 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor H (CFH) (AA 1-449) antibodyCFH 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor H (CFH) (AA 751-780), (Middle Region) antibodyCFH 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- For immunohistology and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
- 限制
- 仅限研究用
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- 缓冲液
- PBS, containing 1.0 % bovine serum albumin and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
- 有效期
- 12 months
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- 抗原
- Complement Factor H (CFH)
- 别名
- Factor H (CFH 产品)
- 别名
- AHUS1 antibody, AMBP1 antibody, ARMD4 antibody, ARMS1 antibody, CFHL3 antibody, FH antibody, FHL1 antibody, HF antibody, HF1 antibody, HF2 antibody, HUS antibody, Mud-1 antibody, NOM antibody, Sas-1 antibody, Sas1 antibody, Fh antibody, CFH antibody, im:7147412 antibody, si:ch211-207o17.2 antibody, fH antibody, armd4 antibody, arms1 antibody, cfh antibody, cfhl3 antibody, fhl1 antibody, hf1 antibody, hf2 antibody, hus antibody, complement factor H antibody, complement component factor h antibody, complement factor H-related protein 5 antibody, complement factor H L homeolog antibody, CFH antibody, Cfh antibody, cfh antibody, LOC100399888 antibody, LOC100733902 antibody, cfh.L antibody
- 背景
- Monoclonal antibody 1A2 recognizes mouse complement factor H (CFH). CFH is the first regulatory protein of the alternative pathway of the complement system. There are three pathways of complement activation, classical, alternative, and lectin activation pathway. These pathways converge to form C3/C5 convertases that generate C3a, C3b,C5a, and C5b, each with substantial biologic activity. Complement regulators are necessary to prevent the injudicious production of these mediators and potential injury to self-tissue. The plasma proteins CFH, C4-binding protein and the cell membrane proteins complement receptor 1 (CR1, CD35), decay-accelerating factor (CD55), and membrane co-factor protein (CD46) all are members of the regulators of complement activation family. These proteins have natural affinity for C3b and/or C4b, which confers on them the ability to accelerate the intrinsic decay of C3/C5 convertases and/or act as co-factor for the cleavage and inactivation (i) of C3b and C4b by complement factor I (CFI). Genetic human analyses reveals a clear association of CFH with different human diseases. These include diseases of the kidney, the atypical form of Hemolytic Uremic Syndrome (aHUS) and membranoproliferative glomerulonephritis (MPGN). Furthermore, CFH is associated with age-related macular degeneration (AMD), a disease of the eye. Immunogen Mouse factor H-human IgG fusion protein
- 途径
- Complement System, Cellular Response to Molecule of Bacterial Origin
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