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MAGI1 抗体 (AA 161-260) (Biotin)

MAGI1 适用: 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN2177497
发货至: 中国
  • 抗原 See all MAGI1 抗体
    MAGI1 (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1))
    抗原表位
    • 14
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 161-260
    适用
    • 21
    • 16
    • 2
    大鼠
    宿主
    • 31
    • 4
    克隆类型
    • 33
    • 2
    多克隆
    标记
    • 14
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAGI1 antibody is conjugated to Biotin
    应用范围
    • 30
    • 16
    • 13
    • 13
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MAGI1
    亚型
    IgG
    Top Product
    Discover our top product MAGI1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    MAGI1 (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1))
    别名
    MAGI1/IRSP58 (MAGI1 产品)
    别名
    CNKSR3 antibody, AIP-3 antibody, AIP3 antibody, BAIAP1 antibody, BAP-1 antibody, BAP1 antibody, MAGI-1 antibody, TNRC19 antibody, WWP3 antibody, Baiap1 antibody, Gukmi1 antibody, MAGI1c antibody, Magi-1 antibody, mKIAA4129 antibody, membrane associated guanylate kinase, WW and PDZ domain containing 1 antibody, MAGI1 antibody, Magi1 antibody
    背景

    Synonyms: AIP 3, AIP3, Atrophin 1 interacting protein 3, atrophin-1 interacting protein 3, BAI associated protein 2, BAI1 associated protein 1, BAI1-associated protein 1, BAIAP 1, BAIAP1, BAP 1, BAP1, BAP2, Brain specific angiogenesis inhibitor 1 associated protein 2, Fas ligand associated factor 3, FLAF3,Gukmi1, Insulin receptor substrate p53, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa, IRS 58, IRSP53, IRSp53/58, MAGI 1, MAGI-1, MAGI1c, Membrane associated guanylate kinase inverted 1, membrane associated guanylate kinase inverted-1, membrane associated guanylate kinase WW and PDZ domain containing 1, Protein BAP2, TNRC 19, TNRC19, Trinucleotide repeat containing gene 19, Trinucleotide repeat containing gene 19 protein,trinucleotide repeat-containing gene 19, WW domain containing protein 3, WW domain-containing protein 3, WWP 3, WWP3.

    Background: The membrane-associated guanylate kinase (MAGUK) proteins are concentrated at the membrane-cytoskeletal interface where they facilitate the assembly of multiprotein complexes on the inner surface of the plasma membrane. Three protein-protein interaction modules characteristically define MAGUK related proteins: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. The closely related MAGUK proteins, MAGI-1, MAGI-2 and MAGI-3 (membrane associated guanylate kinase inverted-1 and 2), likewise contain the GuK domain and five PDZ domains, however, the SH3 domain is replaced with a WW domain. The transcripts of MAGI-1 are alternatively spliced to produce three distinct proteins having unique C-terminals. Two variants, MAGI-1a and MAGI-1b, are associated with the membrane and cytosolic fractions and are primarily expressed in the brain. The third isoform, MAGI-1c, encodes for a nuclear localization signal that localizes MAGI-1c to the nucleus, and it is primarily expressed in the liver and kidney. MAGI-2 and MAGI-3 are localized to the plasma membrane, and they contribute to protein scaffolding by associating with the protein phosphatase PTEN.

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