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- 抗原 See all PRDM1 抗体
- PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRDM1 antibody is un-conjugated
- 应用范围
- 请咨询
- 特异性
- Blimp-1 Antibody, pAb, Rabbit detects endogenous levels of human Blimp-1.
- 交叉反应 (详细)
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It is predicted to react with mouse Blimp-1 according to sequence homology.
Reactivity to other species is not tested yet. - 产品特性
- Blimp-1 Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human Blimp-1 (Swiss Prot: O75626).
- 纯化方法
- Immunoaffinity chromatography
- 免疫原
- KLH-coupled synthetic peptide from C-terminal of human Blimp-1
- 亚型
- IgG
- Top Product
- Discover our top product PRDM1 Primary Antibody
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- 说明
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Positive Control: K562, Ramos
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.
- 浓度
- 0.5 mg/mL
- 缓冲液
- Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.
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c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells." in: Nature immunology, Vol. 15, Issue 9, pp. 884-93, (2014) (PubMed).
: "Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile." in: Nature immunology, Vol. 13, Issue 4, pp. 405-11, (2012) (PubMed).
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c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells." in: Nature immunology, Vol. 15, Issue 9, pp. 884-93, (2014) (PubMed).
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- 抗原
- PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
- 别名
- Blimp-1 (PRDM1 产品)
- 背景
- Blimp-1 (B lymphocyte-induced maturation protein) is a nuclear zinc-finger containing transcriptional repressor and plays an important role in terminal B-cell development. Expression of Blimp-1 is sufficient to drive terminal differentiation of BCL1 lymphoma cells into antibody secreting plasma cells, increasing the expression of the cell surface marker Syndecan-1. In addition, Blimp-1 has been found during macrophage differentiation and in a subset of T-cells, which suggests that it may play a wider role in homeostasis and differentiation.
- UniProt
- O75626
- 途径
- Regulation of Muscle Cell Differentiation
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