电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

PRDM1 抗体 (C-Term)

PRDM1 适用: 人 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2017609
发货至: 中国
  • 抗原 See all PRDM1 抗体
    PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
    抗原表位
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 62
    • 18
    • 12
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 41
    • 23
    • 3
    克隆类型
    • 46
    • 21
    多克隆
    标记
    • 45
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRDM1 antibody is un-conjugated
    应用范围
    请咨询
    特异性
    Blimp-1 Antibody, pAb, Rabbit detects endogenous levels of human Blimp-1.
    交叉反应 (详细)
    It is predicted to react with mouse Blimp-1 according to sequence homology.
    Reactivity to other species is not tested yet.
    产品特性
    Blimp-1 Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human Blimp-1 (Swiss Prot: O75626).
    纯化方法
    Immunoaffinity chromatography
    免疫原
    KLH-coupled synthetic peptide from C-terminal of human Blimp-1
    亚型
    IgG
    Top Product
    Discover our top product PRDM1 Primary Antibody
  • 说明

    Positive Control: K562, Ramos

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.
    浓度
    0.5 mg/mL
    缓冲液
    Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.
  • Chou, Pinto, Curtis, Persaud, Cella, Lin, Edelson, Allen, Colonna, Pearce, Diamond, Egawa: "c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells." in: Nature immunology, Vol. 15, Issue 9, pp. 884-93, (2014) (PubMed).

    Oestreich, Mohn, Weinmann: "Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile." in: Nature immunology, Vol. 13, Issue 4, pp. 405-11, (2012) (PubMed).

  • 抗原
    PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
    别名
    Blimp-1 (PRDM1 产品)
    背景
    Blimp-1 (B lymphocyte-induced maturation protein) is a nuclear zinc-finger containing transcriptional repressor and plays an important role in terminal B-cell development. Expression of Blimp-1 is sufficient to drive terminal differentiation of BCL1 lymphoma cells into antibody secreting plasma cells, increasing the expression of the cell surface marker Syndecan-1. In addition, Blimp-1 has been found during macrophage differentiation and in a subset of T-cells, which suggests that it may play a wider role in homeostasis and differentiation.
    UniProt
    O75626
    途径
    Regulation of Muscle Cell Differentiation
You are here:
客服