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Merlin 抗体 (AA 516-520)

NF2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN197520
发货至: 中国
  • 抗原 See all Merlin (NF2) 抗体
    Merlin (NF2) (Neurofibromin 2 (NF2))
    抗原表位
    • 28
    • 15
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 516-520
    适用
    • 77
    • 65
    • 53
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 88
    • 4
    • 1
    克隆类型
    • 90
    • 3
    多克隆
    标记
    • 47
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This Merlin antibody is un-conjugated
    应用范围
    • 71
    • 30
    • 27
    • 26
    • 19
    • 17
    • 11
    • 11
    • 6
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of total Merlin protein.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    免疫原
    Peptide sequence around aa 516~520 (R-L-S-M-E) derived from Human Merlin
    Top Product
    Discover our top product NF2 Primary Antibody
  • 应用备注
    Western Blot: 1/500approx. 1/1000. Immunohistochemistry on Paraffin-Embedded Sections: 1/50approx. 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    Merlin (NF2) (Neurofibromin 2 (NF2))
    别名
    Merlin (NF2 产品)
    别名
    ACN antibody, BANF antibody, SCH antibody, NF2 antibody, merlin antibody, zgc:194620 antibody, zgc:194631 antibody, NF2a antibody, nf2 antibody, neurofibromin 2 antibody, neurofibromin 2a (merlin) antibody, neurofibromin 2b (merlin) antibody, neurofibromin 2 (merlin) S homeolog antibody, NF2 antibody, Nf2 antibody, nf2a antibody, nf2b antibody, nf2.S antibody
    背景
    Neurofibromin 2 (NF2) is a tumor suppressor gene encoding the protein Merlin. Merlin is closely related to the ERM (ezrin, radixin, moesin) family of proteins. The precise funtion of Merlin is not clear. It is thought to provide a link between the actin cytoskeleten and membrane associated proteins, playing a role in transduction of extracellular signals. It has been implicated in cell proliferation and cellular motility. Mutations in the NF2 gene cause neurofibromatosis type II, a condition characterised by the development of tumors in the central nervous system.Synonyms: Moesin-ezrin-radixin-like protein, NF2, Neurofibromin-2, SCH, Schwannomerlin, Schwannomerlin, Schwannomin, Schwannomin
    基因ID
    4771
    NCBI登录号
    NP_000259
    UniProt
    P35240
    途径
    Cell-Cell Junction Organization
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