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USP11 抗体 (N-Term)

USP11 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1220CT620-193-189 unconjugated
产品编号 ABIN1944797
发货至: 中国
  • 抗原 See all USP11 抗体
    USP11 (Ubiquitin Specific Peptidase 11 (USP11))
    抗原表位
    • 22
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 32-300, N-Term
    适用
    • 62
    • 13
    • 12
    • 1
    • 1
    宿主
    • 57
    • 5
    • 1
    小鼠
    克隆类型
    • 48
    • 15
    单克隆
    标记
    • 29
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This USP11 antibody is un-conjugated
    应用范围
    • 42
    • 33
    • 27
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This USP11 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 32-300 amino acids from the N-terminal region of human USP11.
    克隆位点
    1220CT620-193-189
    亚型
    IgG1 kappa
    Top Product
    Discover our top product USP11 Primary Antibody
  • 应用备注
    WB: 1:1000. FC: 1:25
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Yamaguchi, Kimura, Miki, Yoshida: "The deubiquitinating enzyme USP11 controls an IkappaB kinase alpha (IKKalpha)-p53 signaling pathway in response to tumor necrosis factor alpha (TNFalpha)." in: The Journal of biological chemistry, Vol. 282, Issue 47, pp. 33943-8, (2007) (PubMed).

    Schoenfeld, Apgar, Dolios, Wang, Aaronson: "BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage." in: Molecular and cellular biology, Vol. 24, Issue 17, pp. 7444-55, (2004) (PubMed).

    Ideguchi, Ueda, Tanaka, Yang, Tsuji, Ohno, Hagiwara, Aoki, Ishigatsubo: "Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPM." in: The Biochemical journal, Vol. 367, Issue Pt 1, pp. 87-95, (2002) (PubMed).

    Swanson, Freund, Ploder, McInnes, Valle: "A ubiquitin C-terminal hydrolase gene on the proximal short arm of the X chromosome: implications for X-linked retinal disorders." in: Human molecular genetics, Vol. 5, Issue 4, pp. 533-8, (1996) (PubMed).

  • 抗原
    USP11 (Ubiquitin Specific Peptidase 11 (USP11))
    别名
    USP11 (USP11 产品)
    别名
    USP11 antibody, DKFZp459L098 antibody, UHX1 antibody, 6230415D12Rik antibody, mKIAA4085 antibody, Uhx1 antibody, ubiquitin specific peptidase 11 antibody, universal stress protein antibody, USP11 antibody, RR_RS19935 antibody, Usp11 antibody
    背景
    Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks.
    分子量
    109817
    基因ID
    8237
    UniProt
    P51784
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