MAGED1 抗体 (AA 20-224)
(3 references)-
- 抗原 See all MAGED1 抗体
- MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
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抗原表位
- AA 20-224
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MAGED1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- This MAGED1 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 20-224 amino acids from the Central region of human MAGED1.
- 克隆位点
- 1305CT862-157-127
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product MAGED1 Primary Antibody
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anti-Melanoma Antigen Family D, 1 (MAGED1) (AA 635-834) antibody
MAGED1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) (AA 117-226) antibodyMAGED1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) antibodyMAGED1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) (AA 1-778) antibodyMAGED1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) (AA 579-778) antibodyMAGED1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) (AA 117-226) antibodyMAGED1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) antibodyMAGED1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) (AA 1-778) antibodyMAGED1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) antibodyMAGED1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Antigen Family D, 1 (MAGED1) antibodyMAGED1 适用: 人 WB 宿主: 小鼠 Monoclonal 5C7 unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "hNRAGE, a human neurotrophin receptor interacting MAGE homologue, regulates p53 transcriptional activity and inhibits cell proliferation." in: FEBS letters, Vol. 564, Issue 1-2, pp. 171-6, (2004) (PubMed).
: "NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis." in: Neuron, Vol. 27, Issue 2, pp. 279-88, (2000) (PubMed).
: "Identification of a new, unorthodox member of the MAGE gene family." in: Genomics, Vol. 59, Issue 2, pp. 161-7, (1999) (PubMed).
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: "hNRAGE, a human neurotrophin receptor interacting MAGE homologue, regulates p53 transcriptional activity and inhibits cell proliferation." in: FEBS letters, Vol. 564, Issue 1-2, pp. 171-6, (2004) (PubMed).
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- 抗原
- MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
- 别名
- MAGED1 (MAGED1 产品)
- 别名
- MAGED1 antibody, DLXIN-1 antibody, NRAGE antibody, 2810433C11Rik antibody, 5430405L04Rik antibody, DXBwg1492e antibody, Dlixin antibody, Dlxin-1 antibody, Dlxin1 antibody, MAGE-D1 antibody, mFLJ00163 antibody, Nrage antibody, MAGE family member D1 antibody, melanoma antigen family D, 1 antibody, melanoma antigen, family D, 1 antibody, MAGED1 antibody, Maged1 antibody
- 背景
- Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds NGFR/p75NTR and antagonizes its association with NTRK1/TrkA, inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate TP53/p53 transcriptional activity and inhibit cell proliferation. Enhances TP53 phosphorylation and accumulation. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.
- 分子量
- 86161
- 基因ID
- 9500
- UniProt
- Q9Y5V3
- 途径
- Neurotrophin Signaling Pathway
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