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ZNF536 抗体 (N-Term)

ZNF536 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887978
发货至: 中国
  • 抗原 See all ZNF536 抗体
    ZNF536 (Zinc Finger Protein 536 (ZNF536))
    抗原表位
    • 9
    • 8
    • 6
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 16
    克隆类型
    • 16
    多克隆
    标记
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    This ZNF536 antibody is un-conjugated
    应用范围
    • 16
    • 13
    • 13
    • 13
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    16 amino acid peptide from near the amino terminus of human ZNF536.
    Top Product
    Discover our top product ZNF536 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    ZNF536 (Zinc Finger Protein 536 (ZNF536))
    别名
    ZNF536 (ZNF536 产品)
    别名
    9630010P11Rik antibody, Znf536 antibody, mKIAA0390 antibody, RGD1563363 antibody, zinc finger protein 536 antibody, ZNF536 antibody, Zfp536 antibody
    背景
    ZNF536 is a recently identified zinc-finger protein that is expressed primarily in the developing nervous system and the cerebral cortex, hippocampus, and hypothalamus.ZNF536 possess ten zinc fingers and interacts with CtBP1, a corepressor for gene transcription.It is most closely related to transcriptional repressor ZNF219.Overexpression of ZNF536 in embryonic stem cells dramatically reduced the mRNA levels of neuronal marker genes such as Pax6, MAP2, and beta-tubulin III following retinoic acid (RA)-induced differentiation, while depletion of ZNF536 via RNAi resulted in elevated mRNA levels of these genes, indicating its role in inhibiting neuronal cell differentiation.Overexpression of RA receptor a rescues the inhibitory role of ZNF536, suggesting that ZNF536 might inhibit RA response element-mediated transcriptional activity.
    Synonyms: Zinc finger protein 536
    NCBI登录号
    NP_055532
    途径
    Retinoic Acid Receptor Signaling Pathway
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