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Sonic Hedgehog 抗体 (AA 151-162)

Name: Sonic Hedgehog 抗体 (AA 151-162)
SKU: ABIN1882186
Availability: OutOfStock

SHH 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB46723 unconjugated

Shha Antibody (Center) Azb10041a western blot analysis in zebrafish brain tissue lysate (35 μg/lane).

1 image

(4 references)

产品编号 ABIN1882186

发货至: 中国

Datasheet as PDF

抗原 See all Sonic Hedgehog (SHH) 抗体

Sonic Hedgehog (SHH)
抗原表位
15

11

7

6

4

4

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
AA 151-162
适用
61

54

40

17

8

7

6

5

3

2

2

1

1

1

1

1

1

1
斑马鱼
宿主
72

10

8

1

1
兔
Compatible Secondaries
克隆类型
65

27
多克隆
标记
52

10

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This Sonic Hedgehog antibody is un-conjugated
应用范围
72

32

25

14

13

11

10

8

7

7

5

4

3

1
Western Blotting (WB)

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This shha antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 151-162 amino acids from the Central region of DANRE shha.

克隆位点

RB46723

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anti-Sonic Hedgehog (SHH) (AA 58-91), (N-Term) antibody
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anti-Sonic Hedgehog (SHH) (AA 24-197) antibody
SHH 适用: 人, 大鼠, 犬, 猴 WB, IF 宿主: 小鼠 Monoclonal 10H6 unconjugated

anti-Sonic Hedgehog (SHH) (AA 203-218), (N-Term) antibody
SHH 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Sonic Hedgehog (SHH) (AA 237-399) antibody
SHH 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Müller, Chang, Albert, Fischer, Tora, Strähle: "Intronic enhancers control expression of zebrafish sonic hedgehog in floor plate and notochord." in: Development (Cambridge, England), Vol. 126, Issue 10, pp. 2103-16, (1999) (PubMed).

Zardoya, Abouheif, Meyer: "Evolutionary analyses of hedgehog and Hoxd-10 genes in fish species closely related to the zebrafish." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 23, pp. 13036-41, (1996) (PubMed).

Ekker, Ungar, Greenstein, von Kessler, Porter, Moon, Beachy: "Patterning activities of vertebrate hedgehog proteins in the developing eye and brain." in: Current biology : CB, Vol. 5, Issue 8, pp. 944-55, (1995) (PubMed).

Roelink, Augsburger, Heemskerk, Korzh, Norlin, Ruiz i Altaba, Tanabe, Placzek, Edlund, Jessell: "Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord." in: Cell, Vol. 76, Issue 4, pp. 761-75, (1994) (PubMed).
抗原

Sonic Hedgehog (SHH)

别名

shha (SHH 产品)

别名

HHG1 antibody, HLP3 antibody, HPE3 antibody, MCOPCB5 antibody, SMMCI antibody, TPT antibody, TPTPS antibody, 9530036O11Rik antibody, Dsh antibody, Hhg1 antibody, Hx antibody, Hxl3 antibody, M100081 antibody, fc83d08 antibody, shh antibody, syu antibody, vhh-1 antibody, vhh1 antibody, wu:fc83d08 antibody, Xhh antibody, hedgehog antibody, xshh antibody, SHH antibody, twh antibody, twhh antibody, sonic hedgehog antibody, sonic hedgehog a antibody, sonic hedgehog L homeolog antibody, sonic hedgehog protein A antibody, sonic hedgehog b antibody, SHH antibody, Shh antibody, shha antibody, shh.L antibody, shh antibody, shhb antibody

背景

Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning, dorso-ventral patterning of the brain and early patterning of the developing eyes. Displays floor plate-inducing activity. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO (By similarity).

分子量

46403

UniProt

Q92008

途径

Hedgehog Signaling, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development