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DUSP6 抗体

DUSP6 适用: 大鼠 WB, FACS 宿主: 兔 Polyclonal RB7281 unconjugated
产品编号 ABIN1882185
发货至: 中国
  • 抗原 See all DUSP6 抗体
    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
    适用
    • 91
    • 59
    • 51
    • 2
    • 1
    • 1
    大鼠
    宿主
    • 78
    • 11
    • 2
    • 1
    克隆类型
    • 73
    • 19
    多克隆
    标记
    • 40
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This DUSP6 antibody is un-conjugated
    应用范围
    • 63
    • 35
    • 14
    • 14
    • 11
    • 10
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
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    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein A column, followed by dialysis against PBS.
    免疫原
    This Rat MKP3 antibody is generated from rabbits immunized with a 6xHIS-tagged recombinant protein encoding aa 1~381 of rat MKP3.
    克隆位点
    RB7281
    亚型
    Ig Fraction
    Top Product
    Discover our top product DUSP6 Primary Antibody
  • 应用备注
    WB: 1:1000. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Olson, Protheroe, Segar, Scholz: "Mitogen-activated protein kinase activation and regulation in the pressure-loaded fetal ovine heart." in: American journal of physiology. Heart and circulatory physiology, Vol. 290, Issue 4, pp. H1587-95, (2006) (PubMed).

    Muda, Boschert, Dickinson, Martinou, Martinou, Camps, Schlegel, Arkinstall: "MKP-3, a novel cytosolic protein-tyrosine phosphatase that exemplifies a new class of mitogen-activated protein kinase phosphatase." in: The Journal of biological chemistry, Vol. 271, Issue 8, pp. 4319-26, (1996) (PubMed).

    Mourey, Vega, Campbell, Wenderoth, Hauschka, Krebs, Dixon: "A novel cytoplasmic dual specificity protein tyrosine phosphatase implicated in muscle and neuronal differentiation." in: The Journal of biological chemistry, Vol. 271, Issue 7, pp. 3795-802, (1996) (PubMed).

  • 抗原
    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
    别名
    MKP3 (DUSP6 产品)
    别名
    HH19 antibody, MKP3 antibody, PYST1 antibody, 1300019I03Rik antibody, MKP-3 antibody, Mkp3 antibody, wu:fd99d09 antibody, mkp3 antibody, pyst1 antibody, DUSP6 antibody, dusp6 antibody, dual specificity phosphatase 6 antibody, dual specificity phosphatase 6 L homeolog antibody, Dual specificity protein phosphatase 6 antibody, DUSP6 antibody, Dusp6 antibody, dusp6 antibody, dusp6.L antibody, dus6 antibody
    背景
    Dual specificity protein tyrosine phosphatases (dsPTPs) are a subfamily of protein tyrosine phosphatases implicated in the regulation of mitogen-activated protein kinase (MAPK). MKP-1 (also known as CL100, 3CH134, Erp, and hVH-1) exemplifies a class of dual-specificity phosphatase able to reverse the activation of MAP kinases by dephosphorylating critical tyrosine and threonine residues. MKP-3 is 36 % identical to MKP-1 and it blocks both the phosphorylation and enzymatic activation of ERK2 by mitogens. MKP-3 mRNA is expressed in lung, heart, brain, and kidney, but not significantly in skeletal muscle or testis
    分子量
    42319
    NCBI登录号
    NP_446335
    UniProt
    Q64346
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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