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POLG2 抗体 (C-Term)

POLG2 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB17786 unconjugated
产品编号 ABIN1882118
发货至: 中国
  • 抗原 See all POLG2 抗体
    POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))
    抗原表位
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 348-376, C-Term
    适用
    • 29
    • 9
    • 2
    • 1
    宿主
    • 25
    • 4
    克隆类型
    • 27
    • 2
    多克隆
    标记
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLG2 antibody is un-conjugated
    应用范围
    • 13
    • 11
    • 7
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This POLG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 348-376 amino acids from the C-terminal region of human POLG2.
    克隆位点
    RB17786
    亚型
    Ig Fraction
    Top Product
    Discover our top product POLG2 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Haba, Hatakeyama, Kinoshita, Teramae, Azma, Hatano, Matsuda: "The modulation of vascular ATP-sensitive K+ channel function via the phosphatidylinositol 3-kinase-Akt pathway activated by phenylephrine." in: The Journal of pharmacology and experimental therapeutics, Vol. 334, Issue 2, pp. 673-8, (2010) (PubMed).

    Longley, Clark, Yu Wai Man, Hudson, Durham, Taylor, Nightingale, Turnbull, Copeland, Chinnery: "Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia." in: American journal of human genetics, Vol. 78, Issue 6, pp. 1026-34, (2006) (PubMed).

  • 抗原
    POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))
    别名
    POLG2 (POLG2 产品)
    背景
    The accuracy of mitochondrial DNA (mtDNA) replication depends on the coordinated action of many nuclear-encoded proteins and on the correct balance of nucleotides within the mitochondrial matrix. mtDNA is replicated by DNA polymerase gamma, which is composed of a 140-kD catalytic subunit(POLG1) and a 55-kD accessory subunit (POLG2).
    分子量
    54911
    NCBI登录号
    NP_009146
    UniProt
    Q9UHN1
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