(4 references)-
- 抗原 See all PINK1 抗体
- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
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抗原表位
- AA 237-266
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PINK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This PINK1 (PARK6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-266 amino acids from the Central region of human PINK1 (PARK6).
- 克隆位点
- RB7383
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PINK1 Primary Antibody
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anti-PTEN Induced Putative Kinase 1 (PINK1) (Internal Region) antibody
Verified PINK1 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-273) antibodyPINK1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3A9F8 unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) antibodyPINK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 小鼠 Monoclonal 38CT20-8-5 unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-273) antibodyPINK1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5F2B11 unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibodyPINK1 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S4-15 unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibody (HRP)PINK1 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S4-15 HRP
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibody (FITC)PINK1 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S4-15 FITC
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibody (Alkaline Phosphatase (AP))PINK1 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S4-15 Alkaline Phosphatase (AP)
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibody (Biotin)PINK1 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S4-15 Biotin
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibody (PE)PINK1 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S4-15 PE
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 306, Issue 7, pp. L604-19, (2014) (PubMed).
: "PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1." in: Nature cell biology, Vol. 12, Issue 2, pp. 119-31, (2010) (PubMed).
: "Analysis of the PINK1 gene in a large cohort of cases with Parkinson disease." in: Archives of neurology, Vol. 61, Issue 12, pp. 1898-904, (2004) (PubMed).
: "Novel PINK1 mutations in early-onset parkinsonism." in: Annals of neurology, Vol. 56, Issue 3, pp. 424-7, (2004) (PubMed).
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: "MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 306, Issue 7, pp. L604-19, (2014) (PubMed).
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- 抗原
- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
- 别名
- PINK1 (PARK6) (PINK1 产品)
- 别名
- BEST:GH23468 antibody, CG4523 antibody, Dmel\\CG4523 antibody, PINK antibody, PINK1 antibody, dPINK1 antibody, dPink1 antibody, pink1 antibody, wu:fc39e12 antibody, zgc:101729 antibody, BRPK antibody, PARK6 antibody, 1190006F07Rik antibody, AU042772 antibody, AW557854 antibody, mFLJ00387 antibody, PTEN-induced putative kinase 1 antibody, PTEN induced putative kinase 1 antibody, Pink1 antibody, PINK1 antibody, pink1 antibody
- 背景
- Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6). Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.
- 分子量
- 62769
- NCBI登录号
- NP_115785
- UniProt
- Q9BXM7
- 途径
- Autophagy
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