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CAMKK2 抗体 (C-Term)

Name: CAMKK2 抗体 (C-Term)
SKU: ABIN1882069
Availability: OutOfStock

CAMKK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB12560 unconjugated

Western blot analysis of CKK2 (arrow) using rabbit polyclonal CKK2 Antibody (C-term) (ABIN1882069 and ABIN2841278).

Formalin-fixed and paraffin-embedded human brain tissue reacted with CKK2 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

IHC (p)

2 images

(5 references)

产品编号 ABIN1882069

发货至: 中国

Datasheet as PDF

抗原 See all CAMKK2 抗体

CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
抗原表位
16

9

8

8

5

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 483-512, C-Term
适用
57

36

24

18

17

3

2

2

1

1

1

1

1
人
宿主
59

7
兔
Compatible Secondaries
克隆类型
61

5
多克隆
标记
37

5

4

4

3

2

1

1

1

1

1

1

1

1

1

1

1
This CAMKK2 antibody is un-conjugated
应用范围
61

25

16

14

9

5

4

3

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

M, Rat

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This CAMKK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 483-512 amino acids from the C-terminal region of human CAMKK2.

克隆位点

RB12560

亚型

Ig Fraction

Top Product

Discover our top product CAMKK2 Primary Antibody
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 1-130) antibody
CAMKK2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1A11 unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 1-541) antibody
CAMKK2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 2-137) antibody
CAMKK2 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (C-Term) antibody
CAMKK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (N-Term) antibody
KO Validated CAMKK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (N-Term) antibody
CAMKK2 适用: 人, 小鼠, 大鼠, Pig, 豚鼠, Cow, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 43-71), (N-Term) antibody
CAMKK2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) antibody
CAMKK2 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 239CT7-5-3 unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 483-512) antibody
CAMKK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 52-82) antibody
CAMKK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Wang, Zhang, Liang, Zhang, Xu, Zhang, Fuji, Mu, Li, Jiang, Ju, Wang: "Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin." in: Scientific reports, Vol. 5, pp. 12012, (2015) (PubMed).

Goravanahally, Salem, Yao, Inskeep, Flores: "Differential gene expression in the bovine corpus luteum during transition from early phase to midphase and its potential role in acquisition of luteolytic sensitivity to prostaglandin F2 alpha." in: Biology of reproduction, Vol. 80, Issue 5, pp. 980-8, (2009) (PubMed).

Hsu, Chen, Lee, Chi, Cheng, Chen: "Human Ca2+/calmodulin-dependent protein kinase kinase beta gene encodes multiple isoforms that display distinct kinase activity." in: The Journal of biological chemistry, Vol. 276, Issue 33, pp. 31113-23, (2001) (PubMed).

Hsu, Tsou, Chi, Lee, Chen: "Cloning, expression and chromosomal localization of human Ca2+/calmodulin-dependent protein kinase kinase." in: Journal of biomedical science, Vol. 5, Issue 2, pp. 141-9, (1998) (PubMed).

Anderson, Means, Huang, Kemp, Goldstein, Selbert, Edelman, Fremeau, Means: "Components of a calmodulin-dependent protein kinase cascade. Molecular cloning, functional characterization and cellular localization of Ca2+/calmodulin-dependent protein kinase kinase beta." in: The Journal of biological chemistry, Vol. 273, Issue 48, pp. 31880-9, (1998) (PubMed).
抗原

CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

别名

CAMKK2 (CAMKK2 产品)

别名

CAMKK antibody, CAMKKB antibody, 6330570N16Rik antibody, AW061083 antibody, mKIAA0787 antibody, camk2b antibody, fj90d04 antibody, wu:fj90d04 antibody, si:dkey-174n20.2 antibody, CAMKK2 antibody, calcium/calmodulin dependent protein kinase kinase 2 antibody, calcium/calmodulin-dependent protein kinase kinase 2, beta antibody, calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 antibody, calcium/calmodulin dependent protein kinase II beta antibody, calcium/calmodulin-dependent protein kinase kinase 2 antibody, CAMKK2 antibody, Camkk2 antibody, camk2b1 antibody, CAMK2B antibody, camkk2 antibody

背景

CAMKK2 belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 appears to be involved in hippocampal activation of CREB1.

分子量

64746

NCBI登录号

NP_001257414, NP_001257415, NP_006540, NP_705719, NP_705720, NP_757363, NP_757364, NP_757365, NP_757380

UniProt

Q96RR4

途径

AMPK Signaling