ARL6 抗体 (N-Term)
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- 抗原 See all ARL6 抗体
- ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))
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抗原表位
- AA 1-30, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARL6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This ARL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ARL6.
- 克隆位点
- RB4921
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ARL6 Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Bardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signaling." in: The Journal of biological chemistry, Vol. 285, Issue 21, pp. 16218-30, (2010) (PubMed).
: "Arf, Arl, Arp and Sar proteins: a family of GTP-binding proteins with a structural device for 'front-back' communication." in: EMBO reports, Vol. 3, Issue 11, pp. 1035-41, (2002) (PubMed).
: "A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit." in: FEBS letters, Vol. 459, Issue 1, pp. 69-74, (1999) (PubMed).
: "ADP-ribosylation factor (ARF)-like 4, 6, and 7 represent a subgroup of the ARF family characterization by rapid nucleotide exchange and a nuclear localization signal." in: FEBS letters, Vol. 456, Issue 3, pp. 384-8, (1999) (PubMed).
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Bardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signaling." in: The Journal of biological chemistry, Vol. 285, Issue 21, pp. 16218-30, (2010) (PubMed).
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- 抗原
- ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))
- 别名
- ARL6 (ARL6 产品)
- 别名
- BBS3 antibody, RP55 antibody, 1110018H24Rik antibody, 2210411E14Rik antibody, zgc:101762 antibody, arl6 antibody, ADP ribosylation factor like GTPase 6 antibody, ADP-ribosylation factor-like 6 antibody, ADP-ribosylation factor like GTPase 6 antibody, ADP-ribosylation factor-like protein 6 antibody, ADP ribosylation factor like GTPase 6 L homeolog antibody, ARL6 antibody, Arl6 antibody, arl6 antibody, arl-6 antibody, arl6.L antibody
- 背景
- ARL6 belongs to the ARF family of GTP-binding proteins. ARF proteins are important regulators of cellular traffic and are the founding members of an expanding family of homologous proteins and genomic sequences. They depart from other small GTP-binding proteins by a unique structural device that implements front-back communication from the N-terminus to the nucleotide-binding site. Studies of the mouse ortholog of this protein suggest an involvement in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been described.
- 分子量
- 21097
- NCBI登录号
- NP_001265222, NP_115522, NP_816931
- UniProt
- Q9H0F7
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