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YBX1 抗体 (AA 149-178)

YBX1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB41913 unconjugated
产品编号 ABIN1882002
发货至: 中国
  • 抗原 See all YBX1 抗体
    YBX1 (Y Box Binding Protein 1 (YBX1))
    抗原表位
    • 26
    • 9
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 149-178
    适用
    • 114
    • 76
    • 63
    • 21
    • 19
    • 18
    • 17
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    宿主
    • 105
    • 11
    克隆类型
    • 96
    • 20
    多克隆
    标记
    • 57
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This YBX1 antibody is un-conjugated
    应用范围
    • 82
    • 26
    • 16
    • 15
    • 14
    • 14
    • 13
    • 12
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    预测反应
    B, M, Rb, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This YBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-178 amino acids from the Central region of human YBX1.
    克隆位点
    RB41913
    亚型
    Ig Fraction
    Top Product
    Discover our top product YBX1 Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Osada, Uno, Mineta, Kameoka, Takahashi, Terao: "Ancient genome-wide admixture extends beyond the current hybrid zone between Macaca fascicularis and M. mulatta." in: Molecular ecology, Vol. 19, Issue 14, pp. 2884-95, (2010) (PubMed).

    Yu, Yip, Tan, Thike, Matsumoto, Tsujimoto, Bay: "Y-box binding protein 1 is up-regulated in proliferative breast cancer and its inhibition deregulates the cell cycle." in: International journal of oncology, Vol. 37, Issue 2, pp. 483-92, (2010) (PubMed).

    Lovett, Cheng, Cape, Pollock, Mertens: "YB-1 alters MT1-MMP trafficking and stimulates MCF-7 breast tumor invasion and metastasis." in: Biochemical and biophysical research communications, Vol. 398, Issue 3, pp. 482-8, (2010) (PubMed).

    Takahashi, Shimajiri, Izumi, Hirano, Kashiwagi, Yasuniwa, Wu, Han, Akiyama, Nishizawa, Sasaguri, Kohno: "Y-box binding protein-1 is a novel molecular target for tumor vessels." in: Cancer science, Vol. 101, Issue 6, pp. 1367-73, (2010) (PubMed).

    To, Fotovati, Reipas, Law, Hu, Wang, Astanehe, Davies, Lee, Stratford, Raouf, Johnson, Berquin, Royer, Eaves, Dunn: "Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance." in: Cancer research, Vol. 70, Issue 7, pp. 2840-51, (2010) (PubMed).

  • 抗原
    YBX1 (Y Box Binding Protein 1 (YBX1))
    别名
    YBX1 (YBX1 产品)
    别名
    BP-8 antibody, CSDA2 antibody, CSDB antibody, DBPB antibody, MDR-NF1 antibody, NSEP-1 antibody, NSEP1 antibody, YB-1 antibody, YB1 antibody, Byb1 antibody, Cbfa antibody, Dbpb antibody, Ef1a antibody, Msy1 antibody, Nsep1 antibody, Yb1 antibody, bp-8 antibody, csda2 antibody, csdb antibody, dbpb antibody, frgy1 antibody, mdr-nf1 antibody, nsep-1 antibody, nsep1 antibody, yb1 antibody, 1700102N10Rik antibody, C79409 antibody, EF1A antibody, MSY1 antibody, dbpB antibody, mYB-1a antibody, nuclease sensitive element binding protein 1 antibody, Y-box binding protein 1 antibody, Y box binding protein 1 antibody, Y-box binding protein 1 S homeolog antibody, nuclease-sensitive element-binding protein 1 antibody, Y box protein 1 antibody, nsep1 antibody, YBX1 antibody, Ybx1 antibody, ybx1.S antibody, LOC479011 antibody
    背景
    Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Regulates the transcription of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability.
    分子量
    35924
    NCBI登录号
    NP_004550
    UniProt
    P67809
    途径
    Regulation of Muscle Cell Differentiation
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