SRC 抗体 (V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian)) (N-Term)

Details for Product anti-SRC Antibody No. ABIN1881833, 供应商: Log in to see
抗原
  • AW259666
  • pp60c-src
  • C-src1
  • CG7524
  • D-Src64B
  • D-src
  • DSRC64
  • DSrc
  • DSrc64
  • DSrc64B
  • Dm SRC1
  • DmHD-358
  • Dmel\CG7524
  • Dsrc
  • Dsrc64
  • Dsrc64B
  • HD-358
  • MRE5
  • SRC 64B
  • Src
  • Src1
  • Src64
  • c-src
  • dSrc
  • dsrc
  • src
  • src1
  • src64
  • src64B
  • src64b
  • ASV
  • SRC1
  • c-SRC
  • p60-Src
  • c-Src
  • PP60C-SCR
  • SDR
  • SRC proto-oncogene, non-receptor tyrosine kinase
  • uncharacterized LOC5574802
  • proto-oncogene tyrosine-protein kinase src
  • Rous sarcoma oncogene
  • Src oncogene at 64B
  • SRC
  • LOC5574802
  • CpipJ_CPIJ010659
  • Src
  • Src64B
抗原表位
N-Term, AA 24-52
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适用

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宿主

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克隆类型 (克隆位点)
多克隆 ()
标记
This SRC antibody is un-conjugated
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应用范围
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
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选项
Supplier
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免疫原 This SRC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human SRC.
克隆位点 RB41141
预测反应 Mouse (Murine)
纯化方法 This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
别名 SRC (SRC Antibody 摘要)
背景 This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Synonyms: SRC, SRC1, Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, pp60c-src
NCBI登录号 NP_938033, NP_005408
UniProt P12931
途径 JAK/STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
应用备注 WB: 1:2000,IHC: 1:50,FACS: 1:50,IF: 1:50
限制 仅限研究用
状态 Liquid
浓度 0.5 mg/mL
缓冲液 Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液 Sodium azide
注意事项 WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
厂商提供的图像
Western Blotting (WB) image for anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) (AA 24-52), (N-Term) antibody (ABIN1881833) SRC Antibody (N-term) (ABIN1881833) western blot analysis in MCF-7,A431 cell line lys...
Immunohistochemistry (IHC) image for anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) (AA 24-52), (N-Term) antibody (ABIN1881833) SRC Antibody (N-term) (ABIN1881833) western blot analysis in MCF-7,A431 cell line lys...
Immunohistochemistry (IHC) image for anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) (AA 24-52), (N-Term) antibody (ABIN1881833) SRC Antibody (N-term) (ABIN1881833) western blot analysis in MCF-7,A431 cell line lys...
Flow Cytometry (FACS) image for anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) (AA 24-52), (N-Term) antibody (ABIN1881833) SRC Antibody (N-term) (ABIN1881833) western blot analysis in MCF-7,A431 cell line lys...
Immunofluorescence (IF) image for anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) (AA 24-52), (N-Term) antibody (ABIN1881833) SRC Antibody (N-term) (ABIN1881833) western blot analysis in MCF-7,A431 cell line lys...
Immunofluorescence (IF) image for anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) (AA 24-52), (N-Term) antibody (ABIN1881833) SRC Antibody (N-term) (ABIN1881833) western blot analysis in MCF-7,A431 cell line lys...
有引用在: Kieslinger, Hiechinger, Dobreva, Consalez, Grosschedl: "Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner." in: Cell stem cell, Vol. 7, Issue 4, pp. 496-507, 2010 (PubMed).

Pradhan, Alrehani, Patel, Khatlani, Vijayan: "Cross-talk between serine/threonine protein phosphatase 2A and protein tyrosine phosphatase 1B regulates Src activation and adhesion of integrin αIIbβ3 to fibrinogen." in: The Journal of biological chemistry, Vol. 285, Issue 38, pp. 29059-68, 2010 (PubMed).

Dergai, Tsyba, Dergai, Zlatskii, Skrypkina, Kovalenko, Rynditch: "Microexon-based regulation of ITSN1 and Src SH3 domains specificity relies on introduction of charged amino acids into the interaction interface." in: Biochemical and biophysical research communications, Vol. 399, Issue 2, pp. 307-12, 2010 (PubMed).

Liu, Qiu, Li, Chen, Cao et al.: "Human phosphatidylethanolamine-binding protein 4 promotes transactivation of estrogen receptor alpha (ERalpha) in human cancer cells by inhibiting proteasome-dependent ERalpha degradation via ..." in: The Journal of biological chemistry, Vol. 285, Issue 29, pp. 21934-42, 2010 (PubMed).

Pene-Dumitrescu, Smithgall: "Expression of a Src family kinase in chronic myelogenous leukemia cells induces resistance to imatinib in a kinase-dependent manner." in: The Journal of biological chemistry, Vol. 285, Issue 28, pp. 21446-57, 2010 (PubMed).

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