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- 抗原 See all SPIB 抗体
- SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
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抗原表位
- AA 216-245, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPIB antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- M, Rat
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This SPIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-245 amino acids from the C-terminal region of human SPIB.
- 克隆位点
- RB40547
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SPIB Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis...." in: Nature genetics, Vol. 42, Issue 8, pp. 658-60, (2010) (PubMed).
: "Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression." in: Blood, Vol. 112, Issue 5, pp. 1804-12, (2008) (PubMed).
: "Development of human plasmacytoid dendritic cells depends on the combined action of the basic helix-loop-helix factor E2-2 and the Ets factor Spi-B." in: European journal of immunology, Vol. 38, Issue 9, pp. 2389-400, (2008) (PubMed).
: "Delta-like1-induced Notch1 signaling regulates the human plasmacytoid dendritic cell versus T-cell lineage decision through control of GATA-3 and Spi-B." in: Blood, Vol. 107, Issue 6, pp. 2446-52, (2006) (PubMed).
: "c-Myb and members of the c-Ets family of transcription factors act as molecular switches to mediate opposite steroid regulation of the human glucocorticoid receptor 1A promoter." in: The Journal of biological chemistry, Vol. 280, Issue 52, pp. 43264-71, (2005) (PubMed).
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Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis...." in: Nature genetics, Vol. 42, Issue 8, pp. 658-60, (2010) (PubMed).
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- 抗原
- SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
- 别名
- SPIB (SPIB 产品)
- 背景
- SPI1 (MIM 165170) and SPIB are members of a subfamily of ETS (see ETS1, MIM 164720) transcription factors. ETS proteins share a conserved ETS domain that mediates specific DNA binding. SPIB and SPI1 bind to a purine-rich sequence, the PU box (5-prime-GAGGAA-3-prime).
- 分子量
- 28819
- NCBI登录号
- NP_001230927, NP_001230928, NP_001230929, NP_003112
- UniProt
- Q01892
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