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SPIB 抗体 (C-Term)

SPIB 适用: 人 WB 宿主: 兔 Polyclonal RB40547 unconjugated
产品编号 ABIN1881823
发货至: 中国
  • 抗原 See all SPIB 抗体
    SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
    抗原表位
    • 15
    • 12
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 216-245, C-Term
    适用
    • 24
    • 21
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    宿主
    • 35
    • 1
    • 1
    克隆类型
    • 36
    • 1
    多克隆
    标记
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPIB antibody is un-conjugated
    应用范围
    • 36
    • 18
    • 13
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    预测反应
    M, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SPIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-245 amino acids from the C-terminal region of human SPIB.
    克隆位点
    RB40547
    亚型
    Ig Fraction
    Top Product
    Discover our top product SPIB Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Liu, Invernizzi, Lu, Kosoy, Lu, Bianchi, Podda, Xu, Xie, Macciardi, Selmi, Lupoli, Shigeta, Ransom, Lleo, Lee, Mason, Myers, Peltekian, Ghent, Bernuzzi, Zuin, Rosina, Borghesio, Floreani et al.: "Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis...." in: Nature genetics, Vol. 42, Issue 8, pp. 658-60, (2010) (PubMed).

    Schmidlin, Diehl, Nagasawa, Scheeren, Schotte, Uittenbogaart, Spits, Blom: "Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression." in: Blood, Vol. 112, Issue 5, pp. 1804-12, (2008) (PubMed).

    Nagasawa, Schmidlin, Hazekamp, Schotte, Blom: "Development of human plasmacytoid dendritic cells depends on the combined action of the basic helix-loop-helix factor E2-2 and the Ets factor Spi-B." in: European journal of immunology, Vol. 38, Issue 9, pp. 2389-400, (2008) (PubMed).

    Dontje, Schotte, Cupedo, Nagasawa, Scheeren, Gimeno, Spits, Blom: "Delta-like1-induced Notch1 signaling regulates the human plasmacytoid dendritic cell versus T-cell lineage decision through control of GATA-3 and Spi-B." in: Blood, Vol. 107, Issue 6, pp. 2446-52, (2006) (PubMed).

    Geng, Vedeckis: "c-Myb and members of the c-Ets family of transcription factors act as molecular switches to mediate opposite steroid regulation of the human glucocorticoid receptor 1A promoter." in: The Journal of biological chemistry, Vol. 280, Issue 52, pp. 43264-71, (2005) (PubMed).

  • 抗原
    SPIB (Spi-B Transcription Factor (Spi-1/PU.1 Related) (SPIB))
    别名
    SPIB (SPIB 产品)
    背景
    SPI1 (MIM 165170) and SPIB are members of a subfamily of ETS (see ETS1, MIM 164720) transcription factors. ETS proteins share a conserved ETS domain that mediates specific DNA binding. SPIB and SPI1 bind to a purine-rich sequence, the PU box (5-prime-GAGGAA-3-prime).
    分子量
    28819
    NCBI登录号
    NP_001230927, NP_001230928, NP_001230929, NP_003112
    UniProt
    Q01892
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