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PSMD5 抗体 (C-Term)

PSMD5 适用: 人 WB 宿主: 兔 Polyclonal RB40968 unconjugated
产品编号 ABIN1881699
发货至: 中国
  • 抗原 See all PSMD5 抗体
    PSMD5 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 5 (PSMD5))
    抗原表位
    • 13
    • 11
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 428-457, C-Term
    适用
    • 40
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 35
    • 5
    克隆类型
    • 37
    • 3
    多克隆
    标记
    • 19
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMD5 antibody is un-conjugated
    应用范围
    • 26
    • 18
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    预测反应
    B, M
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This PSMD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the C-terminal region of human PSMD5.
    克隆位点
    RB40968
    亚型
    Ig Fraction
    Top Product
    Discover our top product PSMD5 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Roelofs, Park, Haas, Tian, McAllister, Huo, Lee, Zhang, Shi, Gygi, Finley: "Chaperone-mediated pathway of proteasome regulatory particle assembly." in: Nature, Vol. 459, Issue 7248, pp. 861-5, (2009) (PubMed).

    Kaneko, Hamazaki, Iemura, Sasaki, Furuyama, Natsume, Tanaka, Murata: "Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones." in: Cell, Vol. 137, Issue 5, pp. 914-25, (2009) (PubMed).

    Listovsky, Oren, Yudkovsky, Mahbubani, Weiss, Lebendiker, Brandeis: "Mammalian Cdh1/Fzr mediates its own degradation." in: The EMBO journal, Vol. 23, Issue 7, pp. 1619-26, (2004) (PubMed).

  • 抗原
    PSMD5 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 5 (PSMD5))
    别名
    PSMD5 (PSMD5 产品)
    别名
    S5B antibody, 1500032A03Rik antibody, AW475925 antibody, S5b antibody, W91691 antibody, mKIAA0072 antibody, proteasome 26S subunit, non-ATPase 5 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 antibody, PSMD5 antibody, Psmd5 antibody
    背景
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator base.
    分子量
    56196
    NCBI登录号
    NP_001257356, NP_005038
    UniProt
    Q16401
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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