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KRT6A 抗体 (AA 212-240)

KRT6A 适用: 小鼠 WB 宿主: 兔 Polyclonal RB40714 unconjugated
产品编号 ABIN1881486
发货至: 中国
  • 抗原 See all KRT6A 抗体
    KRT6A (Keratin 6A (KRT6A))
    抗原表位
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 212-240
    适用
    • 64
    • 20
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 59
    • 16
    • 1
    克隆类型
    • 58
    • 18
    多克隆
    标记
    • 37
    • 12
    • 9
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KRT6A antibody is un-conjugated
    应用范围
    • 55
    • 38
    • 25
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Mouse Krt6a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-240 amino acids from the Central region of mouse Krt6a.
    克隆位点
    RB40714
    亚型
    IgG
    Top Product
    Discover our top product KRT6A Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Sehic, Khuu, Risnes, Osmundsen et al.: "Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of..." in: European journal of oral sciences, Vol. 117, Issue 2, pp. 93-104, (2009) (PubMed).

    Chen, Jaeger, Den, Koch, Sundberg, Roop: "Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita." in: The Journal of investigative dermatology, Vol. 128, Issue 2, pp. 270-9, (2008) (PubMed).

    Cui, Kunisada, Esibizione, Grivennikov, Piao, Nedospasov, Schlessinger: "Lymphotoxin-beta regulates periderm differentiation during embryonic skin development." in: Human molecular genetics, Vol. 16, Issue 21, pp. 2583-90, (2007) (PubMed).

    Gu, Coulombe: "Keratin expression provides novel insight into the morphogenesis and function of the companion layer in hair follicles." in: The Journal of investigative dermatology, Vol. 127, Issue 5, pp. 1061-73, (2007) (PubMed).

    Kurek, Garinis, van Doorninck, van der Wees, Grosveld: "Transcriptome and phenotypic analysis reveals Gata3-dependent signalling pathways in murine hair follicles." in: Development (Cambridge, England), Vol. 134, Issue 2, pp. 261-72, (2006) (PubMed).

  • 抗原
    KRT6A (Keratin 6A (KRT6A))
    别名
    Krt6a (KRT6A 产品)
    背景
    Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation related keratins). Keratin 6 is found in hair follicles, neck squamous cell carcinomas, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation. There are at least six isoforms of human type II keratin 6 (K6), K6A being the most abundant representing about 77 % of all forms found in epithelia.
    分子量
    59335
    NCBI登录号
    NP_032502
    UniProt
    P50446
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