电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

ISCU 抗体 (C-Term)

ISCU 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB35591 unconjugated
产品编号 ABIN1881467
发货至: 中国
  • 抗原 See all ISCU 抗体
    ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
    抗原表位
    • 13
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 138-167, C-Term
    适用
    • 31
    • 13
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 27
    • 4
    克隆类型
    • 27
    • 3
    多克隆
    标记
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    This ISCU antibody is un-conjugated
    应用范围
    • 25
    • 22
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This ISCU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the C-terminal region of human ISCU.
    克隆位点
    RB35591
    亚型
    Ig Fraction
    Top Product
    Discover our top product ISCU Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Okerlund, Kivimäe, Tong, Peng, Ullian, Cheyette: "Dact1 is a postsynaptic protein required for dendrite, spine, and excitatory synapse development in the mouse forebrain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 12, pp. 4362-8, (2010) (PubMed).

    Chan, Zhang, Hemann, Mahoney, Zweier, Loscalzo: "MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2." in: Cell metabolism, Vol. 10, Issue 4, pp. 273-84, (2009) (PubMed).

    Kollberg, Tulinius, Melberg, Darin, Andersen, Holmgren, Oldfors, Holme: "Clinical manifestation and a new ISCU mutation in iron-sulphur cluster deficiency myopathy." in: Brain : a journal of neurology, Vol. 132, Issue Pt 8, pp. 2170-9, (2009) (PubMed).

    Huang, Dizin, Cowan: "Mapping iron binding sites on human frataxin: implications for cluster assembly on the ISU Fe-S cluster scaffold protein." in: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 13, Issue 5, pp. 825-36, (2008) (PubMed).

    Mochel, Knight, Tong, Hernandez, Ayyad, Taivassalo, Andersen, Singleton, Rouault, Fischbeck, Haller: "Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance." in: American journal of human genetics, Vol. 82, Issue 3, pp. 652-60, (2008) (PubMed).

  • 抗原
    ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
    别名
    ISCU (ISCU 产品)
    背景
    Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.
    分子量
    17999
    NCBI登录号
    NP_055116, NP_998760
    UniProt
    Q9H1K1
You are here:
客服