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GTPBP3 抗体 (AA 293-320)

GTPBP3 适用: 人 WB 宿主: 兔 Polyclonal RB40710 unconjugated
产品编号 ABIN1881398
发货至: 中国
  • 抗原 See all GTPBP3 抗体
    GTPBP3 (GTP Binding Protein 3 (Mitochondrial) (GTPBP3))
    抗原表位
    • 6
    • 1
    • 1
    • 1
    • 1
    AA 293-320
    适用
    • 13
    • 1
    • 1
    宿主
    • 12
    • 1
    克隆类型
    • 13
    多克隆
    标记
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    This GTPBP3 antibody is un-conjugated
    应用范围
    • 12
    • 10
    • 4
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This GTPBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-320 amino acids from the Central region of human GTPBP3.
    克隆位点
    RB40710
    亚型
    Ig Fraction
    Top Product
    Discover our top product GTPBP3 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Reiling, van Vliet-Ostaptchouk, van t Riet, van Haeften, Arp, Hansen, Kremer, Groenewoud, van Hove, Romijn, Smit, Nijpels, Heine, Uitterlinden, Pedersen, Slagboom, Maassen, Hofker, t Hart, Dekker: "Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study." in: European journal of human genetics : EJHG, Vol. 17, Issue 8, pp. 1056-62, (2009) (PubMed).

    Villarroya, Prado, Esteve, Soriano, Aguado, Pérez-Martínez, Martínez-Ferrandis, Yim, Victor, Cebolla, Montaner, Knecht, Armengod: "Characterization of human GTPBP3, a GTP-binding protein involved in mitochondrial tRNA modification." in: Molecular and cellular biology, Vol. 28, Issue 24, pp. 7514-31, (2008) (PubMed).

    Bykhovskaya, Mengesha, Wang, Yang, Estivill, Shohat, Fischel-Ghodsian: "Phenotype of non-syndromic deafness associated with the mitochondrial A1555G mutation is modulated by mitochondrial RNA modifying enzymes MTO1 and GTPBP3." in: Molecular genetics and metabolism, Vol. 83, Issue 3, pp. 199-206, (2004) (PubMed).

    Li, Guan: "Identification and characterization of mouse GTPBP3 gene encoding a mitochondrial GTP-binding protein involved in tRNA modification." in: Biochemical and biophysical research communications, Vol. 312, Issue 3, pp. 747-54, (2003) (PubMed).

    Li, Guan: "A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation." in: Molecular and cellular biology, Vol. 22, Issue 21, pp. 7701-11, (2002) (PubMed).

  • 抗原
    GTPBP3 (GTP Binding Protein 3 (Mitochondrial) (GTPBP3))
    别名
    GTPBP3 (GTPBP3 产品)
    别名
    GTPBP3 antibody, zgc:112394 antibody, 2410009F13Rik antibody, AI607903 antibody, GTPBG3 antibody, MSS1 antibody, MTGP1 antibody, THDF1 antibody, GTP binding protein 3, mitochondrial antibody, GTP binding protein 3 antibody, GTPBP3 antibody, Gtpbp3 antibody, gtpbp3 antibody
    背景
    This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.
    分子量
    52058
    NCBI登录号
    NP_001122327, NP_001182351, NP_116009, NP_598399
    UniProt
    Q969Y2
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