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COL10A1 抗体 (N-Term)

COL10A1 适用: 人 WB 宿主: 兔 Polyclonal RB40406 unconjugated
产品编号 ABIN1881220
发货至: 中国
  • 抗原 See all COL10A1 抗体
    COL10A1 (Collagen, Type X, alpha 1 (COL10A1))
    抗原表位
    • 6
    • 6
    • 6
    • 2
    • 2
    AA 29-58, N-Term
    适用
    • 24
    • 3
    • 2
    宿主
    • 24
    克隆类型
    • 24
    多克隆
    标记
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COL10A1 antibody is un-conjugated
    应用范围
    • 17
    • 16
    • 4
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This COL10A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human COL10A1.
    克隆位点
    RB40406
    亚型
    Ig Fraction
    Top Product
    Discover our top product COL10A1 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Mäkitie, Susic, Cole: "Early-onset metaphyseal chondrodysplasia type Schmid associated with a COL10A1 frame-shift mutation and impaired trimerization of wild-type α1(X) protein chains." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 28, Issue 11, pp. 1497-501, (2010) (PubMed).

    Wang, Qiu, Ma, Xia, Zhu, Zhu: "Expression of Runx2 and type X collagen in vertebral growth plate of patients with adolescent idiopathic scoliosis." in: Connective tissue research, Vol. 51, Issue 3, pp. 188-96, (2010) (PubMed).

    Videman, Saarela, Kaprio, Näkki, Levälahti, Gill, Peltonen, Battié: "Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowing." in: Arthritis and rheumatism, Vol. 60, Issue 2, pp. 470-81, (2009) (PubMed).

    Higashikawa, Saito, Ikeda, Kamekura, Kawamura, Kan, Oshima, Ohba, Ogata, Takeshita, Nakamura, Chung, Kawaguchi: "Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene." in: Arthritis and rheumatism, Vol. 60, Issue 1, pp. 166-78, (2009) (PubMed).

    Zimmermann, Boeuf, Dickhut, Boehmer, Olek, Richter: "Correlation of COL10A1 induction during chondrogenesis of mesenchymal stem cells with demethylation of two CpG sites in the COL10A1 promoter." in: Arthritis and rheumatism, Vol. 58, Issue 9, pp. 2743-53, (2008) (PubMed).

  • 抗原
    COL10A1 (Collagen, Type X, alpha 1 (COL10A1))
    别名
    COL10A1 (COL10A1 产品)
    背景
    This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD).
    分子量
    66158
    NCBI登录号
    NP_000484
    UniProt
    Q03692
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