(1 reference)-
- 抗原 See all CHM 抗体
- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
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抗原表位
- AA 292-320
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHM antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This CHM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-320 amino acids from the Central region of human CHM.
- 克隆位点
- RB42411
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CHM Primary Antibody
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anti-Choroideremia (Rab Escort Protein 1) (CHM) (C-Term) antibody
CHM 适用: 人, 大鼠, 小鼠, 马, Cow, Pig, 犬, 兔, 驴, 山羊, 绵羊, 豚鼠, Hamster, Cat, 猴, 小鸡, Avian WB 宿主: 山羊 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 1-653) antibodyCHM 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 1-80) antibodyCHM 适用: 人, 大鼠, 小鼠, 马, Cow, Pig, 犬, 兔, 驴, 山羊, 绵羊, 豚鼠, Hamster, Cat, 猴, 小鸡, Avian WB 宿主: 山羊 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 35-84) antibodyCHM 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (AA 120-210) antibodyCHM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Choroideremia (Rab Escort Protein 1) (CHM) (N-Term) antibodyCHM 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "Progression of retinal pigment epithelial alterations during long-term follow-up in female carriers of choroideremia and report of a novel CHM mutation." in: Archives of ophthalmology, Vol. 127, Issue 7, pp. 907-12, (2009) (PubMed).
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: "Progression of retinal pigment epithelial alterations during long-term follow-up in female carriers of choroideremia and report of a novel CHM mutation." in: Archives of ophthalmology, Vol. 127, Issue 7, pp. 907-12, (2009) (PubMed).
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- 抗原
- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
- 别名
- CHM (CHM 产品)
- 别名
- CHM antibody, REP1 antibody, DXS540 antibody, GGTA antibody, HSD-32 antibody, REP-1 antibody, TCD antibody, DKFZp459K2154 antibody, tcd antibody, ggta antibody, rep-1 antibody, dxs540 antibody, hsd-32 antibody, MGC68578 antibody, Rep-1 antibody, chm antibody, chm-a antibody, chm-b antibody, chml antibody, CHM, Rab escort protein 1 antibody, choroideremia (Rab escort protein 1) antibody, choroideremia (Rab escort protein 1) L homeolog antibody, choroidermia (RAB escort protein 1) antibody, choroideremia (Rab escort protein 1) S homeolog antibody, CHM antibody, chm antibody, chm.L antibody, Chm antibody, chm.S antibody
- 背景
- This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia, also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternative splicing results in multiple transcript variants encoding different isoforms.
- 分子量
- 73476
- NCBI登录号
- NP_000381, NP_001138886
- UniProt
- P24386
- 途径
- Sensory Perception of Sound
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