电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CLEC7A 抗体 (FITC)

CLEC7A 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 2A11 FITC
产品编号 ABIN181894
发货至: 中国
  • 抗原 See all CLEC7A 抗体
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    适用
    • 57
    • 36
    • 6
    • 1
    小鼠
    宿主
    • 41
    • 17
    • 17
    大鼠
    克隆类型
    • 42
    • 28
    单克隆
    标记
    • 25
    • 11
    • 9
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CLEC7A antibody is conjugated to FITC
    应用范围
    • 43
    • 38
    • 23
    • 22
    • 9
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    特异性
    This antibody recognises beta-glucan receptor, also known as Dectin-1. This antibody inhibits the binding of zymosan to macrophages via the beta-glucan receptor. The low endotoxin version (SM2025LE) is recommended for functional studies.
    纯化方法
    Affinity chromatography on Protein G
    免疫原
    Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1. Spleen cells from immunised Fischer rats were fused with cells of the rat Y3 myeloma cell line.
    克隆位点
    2A11
    亚型
    IgG2b
    Top Product
    Discover our top product CLEC7A Primary Antibody
  • 应用备注
    Flow Cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    别名
    CLEC7A / Dectin-1 (CLEC7A 产品)
    别名
    CLEC7A antibody, BGR antibody, Clecsf12 antibody, beta-GR antibody, CANDF4 antibody, CLECSF12 antibody, DECTIN1 antibody, Clec7b antibody, RGD1565140 antibody, C-type lectin domain containing 7A antibody, C-type lectin domain family 7, member a antibody, CLEC7A antibody, Clec7a antibody
    背景
    Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells. As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens. Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macropahges via the protein tyrosine kinase known as Syk.Synonyms: BGR, Beta-glucan receptor, C-type lectin domain family 7 member A, C-type lectin superfamily member 12, CLECSF12, DC-associated C-type lectin 1, DECTIN1, Dendritic cell-associated C-type lectin 1
    基因ID
    56644
    NCBI登录号
    NP_064392
    UniProt
    Q6QLQ4
    途径
    Activation of Innate immune Response
You are here:
客服