Macrophage Mannose Receptor 1 抗体 (PE)
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- 抗原 See all Macrophage Mannose Receptor 1 (MRC1) 抗体
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This Macrophage Mannose Receptor 1 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody recognises the mannose receptor, a 175 kDa type 1 membrane protein that is also known as CD206. Clone MR5D3 has been reported to be non-inhibitory for the binding of the mannose receptor to carbohydrate ligands.
- 交叉反应 （详细）
- Species reactivity (tested):Mouse.
- 纯化方法
- Affinity Chromatography on Protein G
- 免疫原
- Chimaeric CRD4-7-Fc protein. Spleen cells from immunised Fischer rats were fused with cells of the Y3 myeloma cell line.
- 克隆位点
- MR5D3
- 亚型
- IgG2a
- Top Product
- Discover our top product MRC1 Primary Antibody
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anti-Mannose Receptor, C Type 1 (MRC1) (AA 22-130) antibody
MRC1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5C11 unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibodyMRC1 适用: 人 FACS, WB, IP, ICC, IHC (fro) 宿主: 小鼠 Monoclonal 15-2 unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibodyMRC1 适用: 人 FACS, WB, IP, ICC, IHC (fro), Func 宿主: 小鼠 Monoclonal 15-2 unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibody (PE)MRC1 适用: 人 FACS 宿主: 小鼠 Monoclonal 15-2 PE
anti-Mannose Receptor, C Type 1 (MRC1) (AA 201-300) antibodyMRC1 适用: 人, 小鼠, 大鼠, 犬 FACS, WB, ELISA, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) (Internal Region) antibodyMRC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibody (FITC)MRC1 适用: 人 FACS 宿主: 小鼠 Monoclonal 15-2 FITC
anti-Mannose Receptor, C Type 1 (MRC1) antibody (APC)MRC1 适用: 人 FACS 宿主: 小鼠 Monoclonal 15-2 APC
anti-Mannose Receptor, C Type 1 (MRC1) (AA 225-492) antibodyMRC1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor, C Type 1 (MRC1) antibodyMRC1 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal CL0387 unconjugated
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- 应用备注
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Flow cytometry: use 10 μL of neat antibody to label 10^6 cells in 100 μL. CD206 is expressed weakly at the cell surface. Staining may be increased following membrane permeabilisation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Restore with 1 mL distilled water.
- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS, 0.09 % Sodium Azide, 1 % BSA, 5 % Sucrose
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
- 别名
- CD206 / MRC1 (MRC1 产品)
- 别名
- CD206 antibody, CLEC13D antibody, CLEC13DL antibody, MMR antibody, MRC1L1 antibody, bA541I19.1 antibody, AW259686 antibody, MR antibody, mrc1 antibody, MGC86525 antibody, MRC1 antibody, MRC1L-A antibody, mannose receptor C-type 1 antibody, mannose receptor, C type 1 antibody, mannose receptor C-type 1 L homeolog antibody, mediator of replication checkpoint 1 antibody, MRC1 antibody, Mrc1 antibody, mrc1.L antibody, mrc1 antibody
- 背景
- CD206, also known as macrophage mannose receptor type C (MMR or MRC1), is a type I membrane receptor protein. CD206 is a phagocytic and endocytic receptor that can recognize carbohydrate ligands in target molecules. The extracellular portion of the protein includes eight C-type carbohydrate recognition domains (CRD) which are clustered together to achieve higher affinity binding to saccharides. CD206 is found on macrophages and on endothelial cells of the liver and is the only known example of a C-type lectin that contains multiple C-type CRDs. CD206 mediates the endocytosis of glycoproteins by macrophages and binds high-mannose structures on the surface of potentially pathogenic viruses, fungi and bacteria enabling them to be neutralized by phagocytic engulfment. During inflammation, CD206 is crucial for rapid clearance of several mannose-bearing serum glycoproteins but does not regulate the initiation of inflammation. CD206 is primarily expressed in mature tissue macrophages and immature Dendritic cells, as well as hepatic and lymphatic endothelial cells, retinal pigmental epithelium (RPE) and mesangial cells.Synonyms: C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, CLEC13D, CLEC13DL, MRC1L1, Macrophage mannose receptor, Macrophage mannose receptor 1-like protein 1
- 基因ID
- 17533
- NCBI登录号
- NP_032651
- UniProt
- Q61830
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