FcRn 抗体
(2 references)-
- 抗原 See all FcRn 抗体
- FcRn (IgG receptor FcRn (FcRn))
-
适用
- 人, 小鼠
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This FcRn antibody is un-conjugated
-
应用范围
- ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Cell-ELISA (cELISA)
- 产品特性
- based on recognition of the complete native protein expressed on transfected mammalian cells
- 纯化方法
- Purified, Protein A
- 免疫原
- Antibodies were generated by immunizing mouse FcRn-deficient mice with spleen cells from mice transgenic for human FcRn.
- 克隆位点
- DVN24
- 亚型
- IgG2a
- Top Product
- Discover our top product FcRn Primary Antibody
-
anti-IgG receptor FcRn (FcRn) antibody
FcRn 适用: 人 ELISA, IF, FACS, cELISA, Func 宿主: 小鼠 Monoclonal ADM31 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-297) antibodyFcRn 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-365) antibodyFcRn 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-215) antibodyFcRn 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FCGRT-2932 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-297) antibodyFcRn 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 2B3B11 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-297) antibodyFcRn 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 5F3D1 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 25-300) antibodyFcRn 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-IgG receptor FcRn (FcRn) (N-Term) antibodyFcRn 适用: 人, 小鼠, 绵羊, Cow, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-IgG receptor FcRn (FcRn) (N-Term) antibodyFcRn 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-IgG receptor FcRn (FcRn) (AA 56-291) antibodyFcRn 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Flow cytometry: 1.2 μg/10^6 cells ELISA: 1:200 - 1:400CELISA: 1:200 - 1:400For each application a titration should be performed to determine the optimal concentration.
- 限制
- 仅限研究用
-
- 缓冲液
- phosphate buffered saline, pH 7.2
- 注意事项
- avoid repeated freezing and thawing
- 储存条件
- 4 °C
-
-
- 抗原
- FcRn (IgG receptor FcRn (FcRn))
- Abstract
- FcRn 产品
- 别名
- FCRN antibody, alpha-chain antibody, FcRn antibody, Fc fragment of IgG receptor and transporter antibody, Fc receptor, IgG, alpha chain transporter antibody, FCGRT antibody, Fcgrt antibody
- 背景
-
The MHC class I-like Fc receptor (FcRn) is an intracellular trafficking Fc receptor that is uniquely responsible for the extended serum half-life of antibodies of the IgG subclass and their ability to transport across cellular barriers. By performing these functions, FcRn affects numerous facets of antibody biology and pathobiology. Its critical role in controlling IgG pharmacokinetics has been leveraged for the design of therapeutic antibodies and related biologics. FcRn also traffics serum albumin and is responsible for the enhanced pharmacokinetic properties of albumin-conjugated therapeutics.
Synonyms: IgG receptor FcRn large subunit p51, Neonatal Fc receptor, FCGRT - UniProt
- P55899
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
-
