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- 抗原 See all P2RX7 抗体
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
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抗原表位
- AA 363-595, C-Term
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This P2RX7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Specific for P2X7.
- 纯化方法
- Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.
- 免疫原
- Recombinant cytoplasmic C-terminal tail of mouse P2X7 (aa 363-595).
- Top Product
- Discover our top product P2RX7 Primary Antibody
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- 应用备注
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WB: 1 : 1000 (AP staining)
IP: not tested yet
ICC: not tested yet
IHC: not tested yet - 说明
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Detects mouse protein with higher sensitivity. This antibody detects an additional band at 30 kDa of unknown identity.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
- 缓冲液
- PBS
- 注意事项
- Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.
- 储存条件
- -20 °C
- 储存方法
- Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!
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A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90." in: Autophagy, Vol. 11, Issue 1, pp. 113-30, (2015) (PubMed).
: "P2X7 purinoceptor alterations in dystrophic mdx mouse muscles: relationship to pathology and potential target for treatment." in: Journal of cellular and molecular medicine, Vol. 16, Issue 5, pp. 1026-37, (2012) (PubMed).
: "Expression, assembly and function of novel C-terminal truncated variants of the mouse P2X7 receptor: re-evaluation of P2X7 knockouts." in: British journal of pharmacology, Vol. 165, Issue 4, pp. 978-93, (2012) (PubMed).
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A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90." in: Autophagy, Vol. 11, Issue 1, pp. 113-30, (2015) (PubMed).
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- 抗原
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
- 别名
- P2X7 (P2RX7 产品)
- 别名
- p2xr7 antibody, P2RX7 antibody, P2X7 antibody, AI467586 antibody, P2X(7) antibody, P2X7R antibody, p2x7 antibody, purinergic receptor P2X 7 antibody, purinergic receptor P2X, ligand-gated ion channel, 7 antibody, P2X purinoceptor 7 antibody, P2RX7 antibody, p2rx7 antibody, LOC100458463 antibody, P2rx7 antibody
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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