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PRKAG1 抗体 (AA 230-331)

PRKAG1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 4A1G9 unconjugated
产品编号 ABIN1724935
发货至: 中国
  • 抗原 See all PRKAG1 抗体
    PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
    抗原表位
    • 9
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 230-331
    适用
    • 49
    • 24
    • 7
    宿主
    • 47
    • 2
    小鼠
    克隆类型
    • 46
    • 3
    单克隆
    标记
    • 24
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRKAG1 antibody is un-conjugated
    应用范围
    • 38
    • 30
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human PRKAG1 (AA: 230-331) expressed in E. coli.
    克隆位点
    4A1G9
    亚型
    IgG1
    Top Product
    Discover our top product PRKAG1 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Zaha, Young: "AMP-activated protein kinase regulation and biological actions in the heart." in: Circulation research, Vol. 111, Issue 6, pp. 800-14, (2012) (PubMed).

    Oliveira, Zhang, Solis, Isackson, Bellahcene, Yavari, Pinter, Davies, Ge, Ashrafian, Walker, Carling, Watkins, Casadei, Redwood: "AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes." in: Circulation research, Vol. 110, Issue 9, pp. 1192-201, (2012) (PubMed).

  • 抗原
    PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
    别名
    PRKAG1 (PRKAG1 产品)
    别名
    MGC68503 antibody, zgc:63896 antibody, wu:fa94d09 antibody, wu:fd12h04 antibody, AMPKG antibody, Prkaac antibody, Prkga1 antibody, AA571379 antibody, BB036179 antibody, protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog antibody, protein kinase, AMP-activated, gamma 1 non-catalytic subunit antibody, protein kinase AMP-activated non-catalytic subunit gamma 1 antibody, prkag1.S antibody, prkag1 antibody, PRKAG1 antibody, Prkag1 antibody
    背景

    Description: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. ,

    Aliases: AMPKG

    分子量
    37.6 kDa
    基因ID
    5571
    HGNC
    5571
    途径
    AMPK Signaling, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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