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DARPP32 抗体 (AA 95-204)

PPP1R1B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A4G9 unconjugated
产品编号 ABIN1724915
发货至: 中国
  • 抗原 See all DARPP32 (PPP1R1B) 抗体
    DARPP32 (PPP1R1B) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B))
    抗原表位
    • 33
    • 17
    • 15
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 95-204
    适用
    • 95
    • 83
    • 75
    • 13
    • 12
    • 12
    • 7
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 108
    • 11
    • 1
    • 1
    • 1
    • 1
    小鼠
    克隆类型
    • 103
    • 20
    单克隆
    标记
    • 72
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DARPP32 antibody is un-conjugated
    应用范围
    • 93
    • 38
    • 35
    • 28
    • 27
    • 18
    • 17
    • 8
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human PPP1R1B (AA: 95-204) expressed in E. coli.
    克隆位点
    2A4G9
    亚型
    IgG1
    Top Product
    Discover our top product PPP1R1B Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Kunii, Ikemoto, Wada, Yang, Kusakabe, Suzuki, Niwa: "Detailed DARPP-32 expression profiles in postmortem brains from patients with schizophrenia: an immunohistochemical study." in: Medical molecular morphology, Vol. 44, Issue 4, pp. 190-9, (2011) (PubMed).

    Hamel, Bouchard, Ferrario, Hassan, Aguilar-Mahecha, Buchanan, Quenneville, Miller, Basik: "Both t-Darpp and DARPP-32 can cause resistance to trastuzumab in breast cancer cells and are frequently expressed in primary breast cancers." in: Breast cancer research and treatment, Vol. 120, Issue 1, pp. 47-57, (2010) (PubMed).

  • 抗原
    DARPP32 (PPP1R1B) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B))
    别名
    PPP1R1B (PPP1R1B 产品)
    别名
    darpp32 antibody, darpp-32 antibody, Darpp-32 antibody, Darpp32 antibody, DARPP-32 antibody, DARPP32 antibody, AU040756 antibody, protein phosphatase 1 regulatory inhibitor subunit 1B antibody, protein phosphatase 1, regulatory (inhibitor) subunit 1B antibody, protein phosphatase 1 regulatory inhibitor subunit 1B S homeolog antibody, ppp1r1b antibody, PPP1R1B antibody, Ppp1r1b antibody, ppp1r1b.S antibody
    背景

    Description: This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. ,

    Aliases: DARPP32, DARPP-32

    分子量
    23 kDa
    基因ID
    84152
    HGNC
    84152
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