ABCG5 抗体 (AA 306-367)
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- 抗原 See all ABCG5 抗体
- ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))
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抗原表位
- AA 306-367
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ABCG5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human ABCG5 (AA: 306-367) expressed in E. coli.
- 克隆位点
- 1B5E10
- 亚型
- IgG1
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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ATP-binding cassette transporter G5 and G8 polymorphisms and several environmental factors with serum lipid levels." in: PLoS ONE, Vol. 7, Issue 5, pp. e37972, (2012) (PubMed).
: "Bile acids stimulate ATP hydrolysis in the purified cholesterol transporter ABCG5/G8." in: Biochemistry, Vol. 49, Issue 16, pp. 3403-11, (2010) (PubMed).
: "
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ATP-binding cassette transporter G5 and G8 polymorphisms and several environmental factors with serum lipid levels." in: PLoS ONE, Vol. 7, Issue 5, pp. e37972, (2012) (PubMed).
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- 抗原
- ABCG5 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))
- 别名
- ABCG5 (ABCG5 产品)
- 别名
- DDBDRAFT_0205617 antibody, DDBDRAFT_0215344 antibody, DDB_0205617 antibody, DDB_0215344 antibody, STSL antibody, AW112016 antibody, cmp antibody, sterolin-1 antibody, trac antibody, ATP binding cassette subfamily G member 5 antibody, ATP-binding cassette, sub-family G (WHITE), member 5 antibody, ABC transporter G family protein antibody, ABCG5 antibody, abcg5 antibody, abcG5 antibody, Abcg5 antibody
- 背景
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Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. , ,
Aliases: STSL
- 分子量
- 72.5 kDa
- 基因ID
- 64240
- HGNC
- 64240
- 途径
- Lipid Metabolism
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