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C1orf114 抗体 (AA 101-200)

CCDC181 适用: 人, 小鼠 ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1714971
发货至: 中国
  • 抗原 See all C1orf114 (CCDC181) 抗体
    C1orf114 (CCDC181) (Coiled-Coil Domain Containing 181 (CCDC181))
    抗原表位
    • 14
    • 8
    • 4
    AA 101-200
    适用
    • 24
    • 15
    • 1
    人, 小鼠
    宿主
    • 24
    克隆类型
    • 24
    多克隆
    标记
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C1orf114 antibody is un-conjugated
    应用范围
    ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠
    预测反应
    Rat,Cow,Sheep,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human C1orf114
    亚型
    IgG
    Top Product
    Discover our top product CCDC181 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Schwarz, Prieler, Schmid, Grzmil, Neesen: "Ccdc181 is a microtubule-binding protein that interacts with Hook1 in haploid male germ cells and localizes to the sperm tail and motile cilia." in: European journal of cell biology, Vol. 96, Issue 3, pp. 276-288, (2018) (PubMed).

  • 抗原
    C1orf114 (CCDC181) (Coiled-Coil Domain Containing 181 (CCDC181))
    别名
    C1orf114 (CCDC181 产品)
    别名
    C1orf114 antibody, RP1-206D15.2 antibody, 4930455F23Rik antibody, AI427889 antibody, RGD1309708 antibody, coiled-coil domain containing 181 antibody, CCDC181 antibody, Ccdc181 antibody
    背景

    Synonyms: C1orf114, CA114_HUMAN, chromosome 1 open reading frame 114, RP1-206D15.2, Uncharacterized protein C1orf114.

    Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf114 gene product has been provisionally designated C1orf114 pending further characterization.

    基因ID
    57821
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