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GCNT1 抗体 (AA 201-260)

GCNT1 适用: 人, 小鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1714546
发货至: 中国
  • 抗原 See all GCNT1 抗体
    GCNT1 (Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1))
    抗原表位
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 1
    AA 201-260
    适用
    人, 小鼠
    宿主
    • 36
    • 2
    • 1
    克隆类型
    • 39
    多克隆
    标记
    • 14
    • 5
    • 5
    • 5
    • 5
    • 5
    This GCNT1 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Sheep
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GCNT1
    亚型
    IgG
    Top Product
    Discover our top product GCNT1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    GCNT1 (Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1))
    别名
    GCNT1 (GCNT1 产品)
    别名
    C2GNT antibody, C2GNT-L antibody, C2GNT1 antibody, G6NT antibody, NACGT2 antibody, NAGCT2 antibody, 5630400D21Rik antibody, B130048E03 antibody, C2 GlcNAcT antibody, IGnT antibody, core 2 GlcNAc-T antibody, glucosaminyl (N-acetyl) transferase 1, core 2 L homeolog antibody, glucosaminyl (N-acetyl) transferase 1, core 2 antibody, gcnt1.L antibody, GCNT1 antibody, Gcnt1 antibody
    背景

    Synonyms: 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase, Beta-1, Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase, C2GNT, C2GNT L, C2GNT1, C2GnTL, Core 2 branching enzyme, Core 2 GNT, Core 2-branching enzyme, Core2 GlcNAc transferase, Core2-GlcNAc-transferase, GCNT 1, GCNT 1, GCNT1, GCNT1_HUMAN, glucosaminyl N-acetyl transferase 1 core 2, NACGT2.

    Background: GCNT1 is expressed in a variety of cell types, including lymphocytes and mucin-producing cells. Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectins. Downregulation of Selectin ligand expression levels has been shown to inhibit tissue infiltration. Therefore, GCNT1 represents a potential drug target for the treatment of inflammatory disorders and other pathologies involving Selectins.

    基因ID
    2650
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