Hexb Chain B (AA 201-300) 抗体 (HRP)
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- 抗原
- Hexb Chain B
- 抗原表位
- AA 201-300
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
-
标记
- HRP
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Sheep
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human HEXB chain B
- 亚型
- IgG
-
-
- 应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- Hexb Chain B
- 背景
-
Synonyms: Beta hexosaminidase beta chain, Beta hexosaminidase subunit beta, Beta N acetylhexosaminidase, Beta-hexosaminidase subunit beta chain B, Beta-N-acetylhexosaminidase subunit beta, Cervical cancer proto oncogene 7 protein, Cervical cancer proto-oncogene 7 protein, ENC 1AS, HCC 7, HCC-7, HCC7, HEX B, Hexb, HEXB_HUMAN, Hexosaminidase B beta polypeptide, Hexosaminidase B, Hexosaminidase subunit B, HexosaminidaseB, N acetyl beta glucosaminidase, N-acetyl-beta-glucosaminidase subunit beta, HEXB chain B.
Background: Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq, Jul 2008].
- 基因ID
- 3074
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