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GLUD2 抗体 (AA 21-120) (HRP)

GLUD2 适用: 人 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal HRP
产品编号 ABIN1712065
发货至: 中国
  • 抗原 See all GLUD2 抗体
    GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))
    抗原表位
    • 14
    • 14
    • 9
    • 4
    • 4
    • 1
    • 1
    AA 21-120
    适用
    • 49
    • 9
    • 9
    • 5
    • 5
    • 1
    • 1
    • 1
    宿主
    • 45
    • 4
    克隆类型
    • 48
    • 1
    多克隆
    标记
    • 21
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GLUD2 antibody is conjugated to HRP
    应用范围
    • 49
    • 19
    • 13
    • 13
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GLUD2
    亚型
    IgG
    Top Product
    Discover our top product GLUD2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    GLUD2 (Glutamate Dehydrogenase 2 (GLUD2))
    别名
    GLUD2 (GLUD2 产品)
    别名
    GDH2 antibody, GLUDP1 antibody, GLUTAMATE DEHYDROGENASE 2 antibody, T2I1.150 antibody, T2I1_150 antibody, glutamate dehydrogenase 2 antibody, glutamate dehydrogenase 2 antibody, glutamate dehydrogenase antibody, GLUD2 antibody, GDH2 antibody, NP_RS03950 antibody
    背景

    Synonyms: GDH 2, GDH, GDH2, GLUDP1, Glutamate dehydrogenase 2, Glutamate dehydrogenase 2 mitochondrial, Glutamate dehydrogenase pseudogene 1.

    Background: GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family. Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission. GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP. Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood. GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. GLUD2 is expressed in testis and retina, with lower levels found in brain.

    基因ID
    2747
    途径
    Synaptic Membrane
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