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FBXO45 抗体 (AA 110-210) (HRP)

FBXO45 适用: 小鼠, 大鼠 WB, ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal HRP
产品编号 ABIN1711540
发货至: 中国
  • 抗原 See all FBXO45 抗体
    FBXO45 (F-Box Protein 45 (FBXO45))
    抗原表位
    • 14
    • 2
    AA 110-210
    适用
    • 15
    • 15
    • 3
    小鼠, 大鼠
    宿主
    • 17
    克隆类型
    • 17
    多克隆
    标记
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXO45 antibody is conjugated to HRP
    应用范围
    • 16
    • 13
    • 13
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Sheep,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human FBXO45
    亚型
    IgG
    Top Product
    Discover our top product FBXO45 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    FBXO45 (F-Box Protein 45 (FBXO45))
    别名
    FBXO45 (FBXO45 产品)
    别名
    Fbx45 antibody, 2610017J04Rik antibody, AI463119 antibody, BC026799 antibody, zgc:65875 antibody, 3g27 antibody, F-box protein 45 antibody, F-box protein 45 S homeolog antibody, FBXO45 antibody, fbxo45 antibody, Fbxo45 antibody, fbxo45.S antibody
    背景

    Synonyms: F box protein 45, F-box only protein 45, F-box/SPRY domain-containing protein 1, FBSP1_HUMAN, FBX45, fbxo45, hFbxo45.

    Background: Belonging to the F-box family of proteins, FBXO45 is a 286 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IB- and -catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO45 can directly interact with Skp1 p19 and CUL-1. FBXO45 has been shown to be an estrogen-induced gene.

    基因ID
    200933
    UniProt
    P0C2W1
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