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Leupaxin 抗体 (AA 251-350) (Cy5.5)

LPXN 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5.5
产品编号 ABIN1705789
发货至: 中国
  • 抗原 See all Leupaxin (LPXN) 抗体
    Leupaxin (LPXN)
    抗原表位
    • 14
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 251-350
    适用
    • 46
    • 19
    • 11
    • 1
    宿主
    • 45
    • 2
    克隆类型
    • 47
    多克隆
    标记
    • 13
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This Leupaxin antibody is conjugated to Cy5.5
    应用范围
    • 35
    • 21
    • 12
    • 12
    • 5
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Leupaxin
    亚型
    IgG
    Top Product
    Discover our top product LPXN Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Leupaxin (LPXN)
    别名
    Leupaxin (LPXN 产品)
    别名
    LDPL antibody, 4933402K05Rik antibody, A530083L21Rik antibody, AV278559 antibody, MGC140379 antibody, leupaxin antibody, hypothetical protein antibody, Leupaxin antibody, LPXN antibody, Lpxn antibody, lpxn antibody, PAAG_03110 antibody, PGTG_11441 antibody
    背景

    Synonyms: LDLP, LDPL, LPXN, LPXN_HUMAN.

    Background: Leupaxin is a 386 amino acid cytoplasmic protein and member of the paxillin family. Leupaxin is highly expressed in lymphoid tissues such as spleen, lymph node, thymus and appendix, with low expression in bone marrow and fetal liver. Consisting of four leucine-rich LD-motifs at the N-terminus and four LIM domains at the C-terminus, leupaxin associates with a member of the focal adhesion kinase family, PYK2, in lymphoid cells. The leupaxin and PYK2 complex is involved in cell type-specific signaling in which it regulates signaling at sites of adhesion. Leupaxin is a substrate for tyrosine kinase in lymphoid cells and is suggested to participate in and be regulated by tyrosine kinase activity. Leupaxin may be a potential progression marker for a subset of prostate cancer and may act as a novel coactivator of the androgen receptor.

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