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SLC1A6 抗体 (AA 151-250) (Cy5)

SLC1A6 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN1704855
发货至: 中国
  • 抗原 See all SLC1A6 抗体
    SLC1A6 (Solute Carrier Family 1 (High Affinity Aspartate/glutamate Transporter), Member 6 (SLC1A6))
    抗原表位
    • 14
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    适用
    • 44
    • 18
    • 11
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 43
    • 3
    克隆类型
    • 43
    • 3
    多克隆
    标记
    • 14
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC1A6 antibody is conjugated to Cy5
    应用范围
    • 30
    • 15
    • 12
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human EAAT4
    亚型
    IgG
    Top Product
    Discover our top product SLC1A6 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SLC1A6 (Solute Carrier Family 1 (High Affinity Aspartate/glutamate Transporter), Member 6 (SLC1A6))
    别名
    EAAT4 (SLC1A6 产品)
    别名
    SLC1A6 antibody, zgc:171923 antibody, EAAT4 antibody, solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 antibody, solute carrier family 1 member 6 antibody, excitatory amino acid transporter 4-like antibody, SLC1A6 antibody, slc1a6 antibody, LOC100224299 antibody, Slc1a6 antibody
    背景

    Synonyms: Excitatory amino acid transporter 4, High affinity neuronal glutamate transporter, MGC33092, MGC43671, Sodium dependent glutamate/aspartate transporter, Solute carrier family 1 high affinity aspartate/glutamate transporter member 6, Solute carrier family 1 member 6 ,EAA4_HUMAN.

    Background: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.

    基因ID
    6511
    UniProt
    P48664
    途径
    Dicarboxylic Acid Transport
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