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Destrin 抗体 (AA 75-165) (Cy5)

DSTN 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN1704639
发货至: 中国
  • 抗原 See all Destrin (DSTN) 抗体
    Destrin (DSTN) (Destrin (Actin Depolymerizing Factor) (DSTN))
    抗原表位
    • 14
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 75-165
    适用
    • 45
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 40
    • 5
    克隆类型
    • 40
    • 5
    多克隆
    标记
    • 18
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Destrin antibody is conjugated to Cy5
    应用范围
    • 39
    • 22
    • 19
    • 16
    • 12
    • 12
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Monkey
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Destrin
    亚型
    IgG
    Top Product
    Discover our top product DSTN Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Destrin (DSTN) (Destrin (Actin Depolymerizing Factor) (DSTN))
    别名
    Destrin (DSTN 产品)
    别名
    ACTDP antibody, ADF antibody, bA462D18.2 antibody, DSTN antibody, LOC100190417 antibody, adf antibody, actdp antibody, ba462d18.2 antibody, 2610043P17Rik antibody, AU042046 antibody, Dsn antibody, corn1 antibody, sid23p antibody, destrin antibody, destrin, actin depolymerizing factor antibody, destrin antibody, destrin, actin depolymerizing factor S homeolog antibody, DSTN antibody, dstn antibody, Dstn antibody, dstn.S antibody
    背景

    Synonyms: 2610043P17Rik, ACTDP, Actin depolymerizing factor, Actin-depolymerizing factor, ADF, AU042046, bA462D18.2, corn1, DEST_HUMAN, Destrin actin depolymerizing factor, Destrin, DSN, Dstn, Sid 23, sid23p.

    Background: Actin-depolymerizing factor (ADF), also known as destrin, is a member of the ADF/Cofilin/destrin superfamily that has the ability to rapidly depolymerize F-Actin in a stoichiometric manner. The Actin-depolymerizing activity of ADF is reversibly controlled by changes in KCl concentration but is insensitive to calcium concentration. ADF depolymerizes F-Actin by interacting directly with F-Actin protomers. ADF shares 71 % sequence homology with Cofilin, however the two proteins differ in their interaction with Actin. The difference in the function of ADF and Cofilin results from the subtle difference in their amino acid sequence rather than possible differences in posttranslational modifications. As a result of different cleavage sites on ADF and Cofilin, the proteins differ in their overall tertiary folds. Sensitivity to polyphosphoinositides may be a common feature in vitro among Actin-binding proteins such as ADF and Cofilin that can bind to G-Actin and regulate the state of Actin polymerization. ADF and Cofilin are Actin-depolymerizing proteins whose activities are possibly regulated by their phosphorylation/dephosphorylation.

    基因ID
    11034
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