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PRNP 抗体 (AA 51-150) (Cy5)

PRNP 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN1704516
发货至: 中国
  • 抗原 See all PRNP 抗体
    PRNP (Prion Protein (PRNP))
    抗原表位
    • 15
    • 14
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    适用
    • 81
    • 33
    • 25
    • 11
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 81
    • 13
    • 2
    • 2
    克隆类型
    • 73
    • 25
    多克隆
    标记
    • 48
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    This PRNP antibody is conjugated to Cy5
    应用范围
    • 56
    • 32
    • 26
    • 25
    • 16
    • 16
    • 8
    • 7
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Cow,Sheep,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PRNP
    亚型
    IgG
    Top Product
    Discover our top product PRNP Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PRNP (Prion Protein (PRNP))
    别名
    Prion protein PrP (PRNP 产品)
    背景

    Synonyms: AltPrP, ASCR, atal familial insomnia, CD230, CD230 antigen, CJD, Creutzfeld Jakob disease, Gerstmann-Strausler-Scheinker syndrome, GSS, KURU, Major prion protein, MGC26679, p27 30, PRIO_HUMAN, Prion protein, Prion related protein, PRIP, Prni, Prnp, PrP, PrP27 30, PrP27-30, PrP33 35C, PrP33-35C, PrPC, PrPSc, Sinc.

    Background: The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012].

    基因ID
    5621
    UniProt
    P04156
    途径
    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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