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GMEB1 抗体 (AA 301-400) (Cy5)

GMEB1 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN1704502
发货至: 中国
  • 抗原 See all GMEB1 抗体
    GMEB1 (Glucocorticoid Modulatory Element Binding Protein 1 (GMEB1))
    抗原表位
    • 14
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-400
    适用
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 24
    • 2
    克隆类型
    • 24
    • 2
    多克隆
    标记
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GMEB1 antibody is conjugated to Cy5
    应用范围
    • 21
    • 12
    • 12
    • 9
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GMEB1
    亚型
    IgG
    Top Product
    Discover our top product GMEB1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    GMEB1 (Glucocorticoid Modulatory Element Binding Protein 1 (GMEB1))
    别名
    GMEB1 (GMEB1 产品)
    别名
    MGC81052 antibody, GMEB1 antibody, si:ch211-245h7.5 antibody, pif96 antibody, p96pif antibody, MGC147529 antibody, P96PIF antibody, PIF96 antibody, 1110050A04Rik antibody, AI256615 antibody, AI481278 antibody, RGD1563208 antibody, glucocorticoid modulatory element binding protein 1 S homeolog antibody, glucocorticoid modulatory element binding protein 1 antibody, gmeb1.S antibody, GMEB1 antibody, gmeb1 antibody, Gmeb1 antibody
    背景

    Synonyms: DNA binding protein p96P, DNA-binding protein p96P, Glucocorticoid modulatory element binding protein 1, Glucocorticoid modulatory element-binding protein 1, GMEB 1, GMEB-1, Gmeb1, GMEB1_HUMAN, P96P, Parvovirus initiation factor p96, P 96, P p96, P96.

    Background: GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.

    基因ID
    10691
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