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KIT 抗体 (pTyr568, pTyr570) (Cy5)

KIT 适用: 人 WB, FACS 宿主: 兔 Polyclonal Cy5
产品编号 ABIN1704371
发货至: 中国
  • 抗原 See all KIT 抗体
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    抗原表位
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    pTyr568, pTyr570
    适用
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    宿主
    • 596
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    克隆类型
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    多克隆
    标记
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    This KIT antibody is conjugated to Cy5
    应用范围
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    Western Blotting (WB), Flow Cytometry (FACS)
    交叉反应
    预测反应
    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human c-Kit around the phosphorylation site of Tyr568 + Tyr570
    亚型
    IgG
    Top Product
    Discover our top product KIT Primary Antibody
  • 应用备注
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    别名
    c-Kit + (KIT 产品)
    别名
    C-Kit antibody, CD117 antibody, PBT antibody, SCFR antibody, Bs antibody, Fdc antibody, Gsfsco1 antibody, Gsfsco5 antibody, Gsfsow3 antibody, SCO1 antibody, SCO5 antibody, SOW3 antibody, Ssm antibody, Tr-kit antibody, W antibody, c-KIT antibody, c-kit antibody, MGF antibody, KIT antibody, C-KIT antibody, kit antibody, receptor antibody, sparse antibody, Xkl-1 antibody, kit-a antibody, kit-b antibody, kl1-A antibody, krk1 antibody, pbt antibody, scfr antibody, KIT proto-oncogene receptor tyrosine kinase antibody, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a antibody, KIT proto-oncogene receptor tyrosine kinase S homeolog antibody, KIT antibody, Kit antibody, kita antibody, kit antibody, kit.S antibody
    背景

    Synonyms: c-Kit phospho Y568 + Y570, p-c-Kit phospho Y568 + Y570, C Kit, c-Kit, CD 117, CD117, CD117 antigen, KIT, KIT_HUMAN, Mast/stem cell growth factor receptor, Mast/stem cell growth factor receptor Kit, p145 c-kit, PBT, Piebald trait protein, Proto oncogene c Kit, Proto oncogene tyrosine protein kinase Kit, Proto-oncogene c-Kit, SCF Receptor, SCFR, soluble KIT variant 1, Stem cell factor receptor, tyrosine protein kinase Kit, Tyrosine-protein kinase Kit, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog.

    Background: c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.

    基因ID
    3815
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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