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HOOK1 抗体 (AA 551-650) (Cy5)

HOOK1 适用: 小鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN1704320
发货至: 中国
  • 抗原 See all HOOK1 抗体
    HOOK1 (Hook Homolog 1 (HOOK1))
    抗原表位
    • 14
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 551-650
    适用
    • 34
    • 22
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 44
    • 4
    克隆类型
    • 46
    • 2
    多克隆
    标记
    • 21
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HOOK1 antibody is conjugated to Cy5
    应用范围
    • 43
    • 24
    • 12
    • 12
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human HOOK1
    亚型
    IgG
    Top Product
    Discover our top product HOOK1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    HOOK1 (Hook Homolog 1 (HOOK1))
    别名
    HOOK1 (HOOK1 产品)
    别名
    si:dkey-183n20.14 antibody, A930033L17Rik antibody, azh antibody, HK1 antibody, HOOK1 antibody, hook microtubule tethering protein 1 antibody, hook microtubule-tethering protein 1 antibody, HOOK1 antibody, hook1 antibody, Hook1 antibody
    背景

    Synonyms: A930033L17Rik, Abnormal spermatozoon head shape, azh, h-hook1, hHK1, HK1, HOOK 1, Hook homolog 1 Drosophila, Hook1, HOOK1_HUMAN, MGC10642, OTTHUMP00000010548, OTTMUSP00000008480, Protein Hook homolog 1, RP23-80B16.4.

    Background: Microtubules mediate the spatial organization of diverse membrane-trafficking systems. The HOOK proteins, HOOK1, HOOK2 and HOOK3, comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. HOOK1, a cytoskeletal linker protein, may play a role in endocytic membrane trafficking. It exists as a homodimer, most likely mediated through its central coiled-coil domain. HOOK1 interacts with VPS18 and is required for spermatid differentiation, in which it is most likely involved in the positioning of the manchette microtubules and the flagellum. HOOK1 localizes primarily to the cytoplasm and does not associate with the Golgi complex, unlike HOOK3, which participates in the organization of the cis-Golgi compartment.

    基因ID
    51361
    途径
    SARS-CoV-2 Protein Interactome
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