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HIC2 抗体 (AA 501-600) (Cy5)

HIC2 适用: 人 WB, IF (p), IF (cc) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN1704318
发货至: 中国
  • 抗原 See all HIC2 抗体
    HIC2 (Hypermethylated in Cancer 2 (HIC2))
    抗原表位
    • 14
    • 7
    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-600
    适用
    • 54
    • 27
    • 10
    • 7
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 48
    • 5
    • 1
    克隆类型
    • 52
    • 2
    多克隆
    标记
    • 24
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This HIC2 antibody is conjugated to Cy5
    应用范围
    • 45
    • 22
    • 12
    • 12
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human HIC2
    亚型
    IgG
    Top Product
    Discover our top product HIC2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    HIC2 (Hypermethylated in Cancer 2 (HIC2))
    别名
    Hic2 (HIC2 产品)
    别名
    HIC2 antibody, hic2 antibody, MGC154932 antibody, HRG22 antibody, ZBTB30 antibody, ZNF907 antibody, AA409108 antibody, mKIAA1020 antibody, zgc:109776 antibody, HIC ZBTB transcriptional repressor 2 antibody, hypermethylated in cancer 2 L homeolog antibody, hypermethylated in cancer 2 antibody, HIC2 antibody, hic2.L antibody, Hic2 antibody, hic2 antibody
    背景

    Synonyms: HIC1 related gene on chromosome 22, HIC2, Hic3, HRG22, Hypermethylated in cancer 2 protein, KIAA1020, ZBTB30, Zinc finger and BTB domain-containing protein 30, ZNF907, HIC2_HUMAN.

    Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HIC-2 (hypermethylated in cancer 2) possesses zinc finger motifs that are thought to be important for DNA-binding and also has a BTB/POZ domain at the N-terminus, which is thought to be important for protein-protein binding, as well as for the binding of transcription factors. HIC-2 is also known as Hic-3, HIC1-related gene on chromosome 22 or Zinc finger and BTB domain-containing protein 30, and is a 615 amino acid protein that is expressed as two isoforms produced by alternative splicing. HIC-2 is highly expressed in cerebellum and is localized to the nucleus in cells. HIC-2 contains a short amino acid sequence that is thought to interact with CtBP, a transcriptional repressor. The gene sequence associated with HIC-2 is thought to be a target for miRNAs (microRNAs) which are expressed in many cancers, suggesting that HIC-2 could possess tumor suppressor capabilities.

    基因ID
    23119
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