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FIP1L1 抗体 (AA 501-594) (Cy5)

FIP1L1 适用: 人 WB, IF (p), IF (cc) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN1704282
发货至: 中国
  • 抗原 See all FIP1L1 抗体
    FIP1L1 (FIP1 Like 1 (FIP1L1))
    抗原表位
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-594
    适用
    • 25
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 23
    • 2
    克隆类型
    • 23
    • 2
    多克隆
    标记
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FIP1L1 antibody is conjugated to Cy5
    应用范围
    • 25
    • 12
    • 12
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human FIP1L1
    亚型
    IgG
    Top Product
    Discover our top product FIP1L1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    FIP1L1 (FIP1 Like 1 (FIP1L1))
    别名
    FIP1L1 (FIP1L1 产品)
    别名
    FIP1 antibody, Rhe antibody, hFip1 antibody, 1300019H17Rik antibody, Rje antibody, fip1l1 antibody, wu:fd36f11 antibody, zgc:103421 antibody, factor interacting with PAPOLA and CPSF1 antibody, factor interacting with PAPOLA and CPSF1 S homeolog antibody, FIP1 like 1 (S. cerevisiae) antibody, FIP1 like 1b (S. cerevisiae) antibody, fip1l1 antibody, FIP1L1 antibody, fip1l1.S antibody, Fip1l1 antibody, fip1l1b antibody
    背景

    Synonyms: DKFZp586K0717, Factor interacting with PAP, FIP1, FIP1 like 1 S cerevisiae, FIP1 like 1, FLJ33619, hFip 1, hFip1, Pre mRNA 3 end processing factor FIP1, Rearranged in hypereosinophilia, RHE, FIP1_HUMAN.

    Background: The Component of the Cleavage and Polyadenylation Specificity Factor (CPSF) complex plays an important role in the 3'-end formation of pre-mRNA. This complex recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase to process and add to the poly(A) tail. FIP1L1 (FIP1-like 1), also known as Pre-mRNA 3'-end-processing factor FIP1, FIP1 (Factor interacting with PAP) and RHE (Rearranged in hypereosinophilia), is a 594 amino acid nuclear protein that is a component of the CPSF complex. Within the complex, FIP1L1 contributes to the poly(A) recognition and stimulates poly(A) addition. Fusion of the genes encoding FIP1L1 and PDGFRA due to an interstitial deletion on chromosome 4q12 is the cause of hypereosinophilia syndrome, a rare blood disorder characterized by continuous overproduction of eosinophils in the bone marrow that leads to tissue infiltration and organ damage. There are three isoforms of FIP1L1 that are produced as a result of alternative splicing events.

    基因ID
    81608
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