CLCNKB 抗体 (AA 51-150) (Biotin)
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- 抗原 See all CLCNKB 抗体
- CLCNKB (Chloride Channel Kb (CLCNKB))
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抗原表位
- AA 51-150
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CLCNKB antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CLCNKB
- 亚型
- IgG
- Top Product
- Discover our top product CLCNKB Primary Antibody
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anti-Chloride Channel Kb (CLCNKB) (AA 538-687) antibody
CLCNKB 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel Kb (CLCNKB) (N-Term) antibodyCLCNKB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel Kb (CLCNKB) (N-Term) antibodyCLCNKB 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel Kb (CLCNKB) (C-Term) antibodyCLCNKB 适用: 人, 大鼠, 犬, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- CLCNKB (Chloride Channel Kb (CLCNKB))
- 别名
- CLCNKB (CLCNKB 产品)
- 别名
- CLCNKA antibody, CLCNKB antibody, DKFZp469N0132 antibody, CLCKB antibody, Clc-Ka antibody, Clck2 antibody, Clcnk1l antibody, ClC-K2L antibody, ClC-K2 antibody, ClC-Kb antibody, ClC-k antibody, clc-kb antibody, clckb antibody, clcnka-A antibody, clk-k2 antibody, x6clck antibody, xCIC-K antibody, xClC-K antibody, zgc:64141 antibody, Clcnkb antibody, chloride voltage-gated channel Kb antibody, chloride channel Kb antibody, chloride channel, voltage-sensitive Kb antibody, chloride channel, voltage-sensitive Kb L homeolog antibody, chloride channel K antibody, chloride channel protein ClC-Ka antibody, chloride channel protein ClC-Kb antibody, CLCNKB antibody, Clcnkb antibody, clcnkb.L antibody, clcnk antibody, LOC100017912 antibody, LOC100400180 antibody, LOC100590605 antibody, LOC100730738 antibody
- 背景
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Synonyms: Bartter syndrome type 3, Chloride channel Kb, Chloride channel kidney B, Chloride channel protein ClC-Kb, Chloride channel voltage sensitive Kb, ClC K2, ClC-K2, ClCK2, CLCKB, CLCKB_HUMAN, CLCNKB, hClC Kb, hClCKb, MGC24087, OTTHUMP00000011120, OTTHUMP00000011121, RP11 5P18.8.
Background: The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport, and maintain cellular volume. CLC-KA is a kidney-specific chloride channel that mediates transepithelial chloride transport in the thin ascending limb of the Henle loop in the inner medulla. CLC-KA plays a crucial role in urine concentration. The gene encoding human CLC-KA maps to chromosome 1p36. Mutations in this gene may be associated with nephrogenic diabetes insipidus in those cases where mutations in the vasopressin V2 receptor and the AQP2 water channel are lacking. CLC-KB mediates basolateral chloride ion efflux in the thick ascending limb and in more distal nephron segments. The gene encoding human CLC-KB maps to chromosome 1p36. Mutations in this gene cause type III Barter?s syndrome which is characterized by renal salt-wasting and low blood pressure.
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