PTPN23 抗体 (AA 1501-1636) (Alexa Fluor 488)
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- 抗原 See all PTPN23 抗体
- PTPN23 (Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23))
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抗原表位
- AA 1501-1636
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTPN23 antibody is conjugated to Alexa Fluor 488
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Pig,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human HDPTP
- 亚型
- IgG
- Top Product
- Discover our top product PTPN23 Primary Antibody
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anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) (C-Term) antibody
PTPN23 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) (AA 1230-1450) antibodyPTPN23 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) (AA 1501-1636) antibodyPTPN23 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) (AA 1-577) antibodyPTPN23 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) antibodyPTPN23 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PTPN23 (Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23))
- 别名
- Hdptp (PTPN23 产品)
- 别名
- HD-PTP antibody, HDPTP antibody, PTP-TD14 antibody, AI462446 antibody, Ptp-Td14 antibody, ptp23b antibody, si:dkeyp-114f9.2 antibody, protein tyrosine phosphatase, non-receptor type 23 antibody, protein tyrosine phosphatase, non-receptor type 23, b antibody, PTPN23 antibody, Ptpn23 antibody, ptpn23b antibody
- 背景
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Synonyms: DKFZP564F0923, EC 3.1.3.48, HD PTP, HD-PTP, HDPTP, His domain containing protein tyrosine phosphatase, His domain protein tyrosine phosphatase, His domain-containing protein tyrosine phosphatase, KIAA1471, Protein tyrosine phosphatase non receptor type 23, protein tyrosine phosphatase non-receptor type 23, Protein tyrosine phosphatase TD 14, protein tyrosine phosphatase TD14, PTN23_HUMAN, PTP TD14, PTP-TD14, PTPN 23, PTPN23, Tyrosine protein phosphatase non receptor type 23, Tyrosine-protein phosphatase non-receptor type 23.
Background: HD-PTP is a 1,636 amino acid protein encoded by the human gene PTPN23. HD-PTP belongs to the protein-tyrosine phosphatase family, non-receptor class subfamily. It contains one BRO1 domain, two TPR repeats and one tyrosine-protein phosphatase domain. The C-terminal region contains the PTP-like domain, whereas the N-terminal region contains the two TPR regions. These regions are homologous to the yeast protein, BRO1, which is involved in the mitogen-activated protein kinase signaling pathway. Similarly, HD-PTP is believed to act as a negative regulator of Ras-mediated mitogenic activity and is phosphorylated upon DNA damage, probably by ATM or ATR. HD-PTP protein is differentially modulated by two angiogenic growth factors. While Vascular Endothelial Growth Factor (VEGF) has no affect on protein levels, Fibroblast Growth Factor-2 (FGF-2) induces HD-PTP degradation via the proteasome system.
- 基因ID
- 25930
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