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GCS1 抗体 (AA 51-150) (Alexa Fluor 350)

MOGS 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 350
产品编号 ABIN1693684
发货至: 中国
  • 抗原 See all GCS1 (MOGS) 抗体
    GCS1 (MOGS) (Mannosyl-Oligosaccharide Glucosidase (MOGS))
    抗原表位
    • 14
    • 10
    • 9
    • 7
    • 7
    • 1
    • 1
    AA 51-150
    适用
    • 52
    • 14
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 53
    克隆类型
    • 53
    多克隆
    标记
    • 20
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GCS1 antibody is conjugated to Alexa Fluor 350
    应用范围
    • 53
    • 31
    • 12
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GCS1
    亚型
    IgG
    Top Product
    Discover our top product MOGS Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    GCS1 (MOGS) (Mannosyl-Oligosaccharide Glucosidase (MOGS))
    别名
    GCS1 (MOGS 产品)
    别名
    Afu6g04210 antibody, AO090701000141 antibody, Mogs antibody, CDG2B antibody, CWH41 antibody, DER7 antibody, GCS1 antibody, 1810017N02Rik antibody, AI181835 antibody, Gcs1 antibody, gcs1 antibody, im:7160827 antibody, wu:fe50a12 antibody, wu:fk09a10 antibody, zgc:158312 antibody, mannosyl-oligosaccharide glucosidase antibody, mannosyl-oligosaccharide glucosidase GCS1 antibody, mannosyl-oligosaccharide glucosidase L homeolog antibody, mannosyl oligosaccharide glucosidase antibody, glucosidase 1 antibody, AFUA_6G04210 antibody, Tc00.1047053511015.10 antibody, Tc00.1047053511805.10 antibody, LOC5576381 antibody, AOR_1_260114 antibody, MGYG_00305 antibody, TERG_01248 antibody, mogs.L antibody, TTHERM_00636930 antibody, LOAG_03690 antibody, Gcs1 antibody, MOGS antibody, Mogs antibody, mogs antibody
    背景

    Synonyms: EC 3.2.1.106, glucosidase I, Mannosyl oligosaccharide glucosidase, Mannosyl-oligosaccharide glucosidase, Mogs, MOGS_HUMAN, Processing A glucosidase I, Processing A-glucosidase I.

    Background: Glycosylation of asparagine residues in Asn-X-Ser/Thr motifs in proteins commonly occur in the lumen of the endoplasmic reticulum (ER). Glucosidase I catalyzes the first step in the N-linked oligosaccharide processing pathway. It specifically removes the distal alpha 1,2-linked glucose residue from the Glc3-Man9-GlcNAc2 oligosaccharide precursor. Glucosidase I contains a short cytosolic tail, a single pass transmembrane domain and a large C-terminal catalytic domain located on the luminal side of the ER. Mutations in the gene encoding Glucosidase I result in the congenital disorder glycosylation (CDG-IIb), which is characterized by generalized hypotonia, dysmorphic features, hepatomegaly, hypoventilation, feeding problems, seizures and death. Two point mutations in the Glucosidase I gene have been identified and result in amino acid substitutions, namely Arg486Thr and Phe652Leu, that affect polypeptide folding and active site formation.

    基因ID
    7841
    途径
    SARS-CoV-2 Protein Interactome
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